Estimation of gastric cancer burden attributable to Helicobacter pylori infection in Asia.
Background Helicobacter pylori causes large burden of gastric cancer (GC) in Asia. We aimed to comprehensively quantify the burden of GC attributable to H. pylori infection in Asia. Methods We searched related articles from January 1998 to December 2020 to obtain the prevalence and relative risks (o...
| Published in: | Journal of Public Health Vol. 45; no. 1; pp. 40 - 47 |
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| Main Authors: | , , , , , |
| Format: | equations & formulas research systematic review tables/charts Journal Article |
| Published: |
Oxford University Press / USA
Mar2023
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=162442608&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 162442608 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17413842 1CA0 jtl: Journal of Public Health issn: 17413842 maglogo: N pubinfo: dt: Mar2023 vid: 45 iid: 1 pid: 622 pub: Oxford University Press / USA artinfo: ui: 162442608 162442608 162442608 10.1093/pubmed/fdab410 162442608 ppf: 40 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Estimation of gastric cancer burden attributable to Helicobacter pylori infection in Asia. aug: au: Ji, Xuanke He, Gui Wang, Kunyan Zhang, Yuehua Yin, Jingjing Wang, Kaijuan affil: Department of Epidemiology , College of Public Health, Zhengzhou University, Zhengzhou, China sug: subj: Stomach Neoplasms Epidemiology Helicobacter Infections Epidemiology Disease Hotspot Helicobacter Infections Risk Factors Stomach Neoplasms Risk Factors Risk Assessment Human Male Female Funding Source Asia Relative Risk World Health Organization Quality Assessment Odds Ratio Confidence Intervals Chi Square Test Scales Sample Size Proteins Cytokines Adult Middle Age Aged Aged, 80 and Over Systematic Review Meta Analysis PubMed Embase Cochrane Library Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Background Helicobacter pylori causes large burden of gastric cancer (GC) in Asia. We aimed to comprehensively quantify the burden of GC attributable to H. pylori infection in Asia. Methods We searched related articles from January 1998 to December 2020 to obtain the prevalence and relative risks (or odds ratio) of GC associated with H. pylori in Asia. The burden of GC attributable to H. pylori infection was quantified by Population Attributable Fraction (PAF) and Disability-adjusted life-years (DALYs). Results We quantified the burden of GC attributable to H. pylori infection with 415.6 thousand DALYs and 38.03% PAF through the five included Asian countries in 2019. The study found that the burden had obvious regional differences. The DALYs ranged from 298.9 thousand in China to 1.9 thousand in Malaysia, and the PAFs were between 58.00% in Japan and 30.89% in China. The average prevalence of H. pylori in the included general population was estimated to be 56.29%. Conclusions Helicobacter pylori poses a huge disease burden of GC to the population, and its eradication should receive attention, especially in the countries with high incidence of and mortality due to GC. pubtype: Academic Journal doctype: equations & formulas meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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