Trend and risk Factors for Severe Peripartum Maternal morbidity - a population-based Cohort Study.

Objectives: While the rates of maternal mortality in developed countries have remained low in recent years, rates of severe maternal morbidity (SMM) are still increasing in high income countries. As a result, SMM is currently used as a measure of maternity care level. The aim of this study was to in...

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Published in:Maternal & Child Health Journal Vol. 27; no. 4; pp. 719 - 728
Main Authors: Ben-Ayoun, Danielle, Walfisch, Asnat, Wainstock, Tamar, Sheiner, Eyal, Imterat, Majdi
Format: research tables/charts Journal Article
Published: Springer Nature Apr2023
Online Access:View this record in EBSCOhost
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      dt: Apr2023
      vid: 27
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10995-022-03568-2
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        atl: Trend and risk Factors for Severe Peripartum Maternal morbidity - a population-based Cohort Study.
      aug:
        au:
          Ben-Ayoun, Danielle
          Walfisch, Asnat
          Wainstock, Tamar
          Sheiner, Eyal
          Imterat, Majdi
        affil: Faculty of Health Sciences, Ben-Gurion University of the Negev, 151 Izak Rager Ave. Beer-Sheva, 84101, Beer-Sheva, Israel
      sug:
        subj:
          Pregnancy Complications Trends
          Pregnancy Complications Risk Factors
          Risk Assessment
          Morbidity Risk Factors
          Morbidity Trends
          Human
          Prospective Studies
          Case Control Studies
          Intensive Care Units
          Comparative Studies
          Multiple Logistic Regression
          Placenta Praevia
          Childbirth, Premature
          Placenta Accreta
          Parity
          Jews
          Abortion, Spontaneous
          Israel
          Pregnancy
          Female
          Descriptive Statistics
          Data Analysis Software
          Fisher's Exact Test
          Pearson's Correlation Coefficient
          Paired T-Tests
          Mann-Whitney U Test
          Female
      ab: Objectives: While the rates of maternal mortality in developed countries have remained low in recent years, rates of severe maternal morbidity (SMM) are still increasing in high income countries. As a result, SMM is currently used as a measure of maternity care level. The aim of this study was to investigate the prevalence and risk factors of SMM surrounding childbirth. Methods: A nested case-control study was performed between the years 2013–2018. SMM was defined as peripartum hospitalization involving intensive care unit (ICU). A comparison was conducted between parturient with SMM to those without, randomly matched for delivery mode and date of birth in a 1:1 ratio. Multivariable logistic regression models were used to evaluate the independent association between SMM and different maternal and pregnancy characteristics. Results: During the study period, 96,017 live births took place, of which 144 (1.5 per 1,000 live births-0.15%) involved SMM with ICU admissions. Parturient with SMM were more likely to have a history of 2 or more pregnancy losses (18.2% vs. 8.3%, p = 0.004), deliver preterm (48.9% vs. 8.8%, p < 0.001), and suffer from placenta previa (11.9% vs. 1.5%, p < 0.001), and/or placenta accreta (9.7% vs. 1.5%, p = 0.003). Several significant and independent risk factors for SMM were noted in the multivariable regression models: preterm delivery, history of ≥ 2 pregnancy losses, grand-multiparity, Jewish ethnicity, and abnormal placentation (previa or accreta). Conclusions for Practice: SMM rates in our cohort were lower than reported in developed countries. An independent association exists between peripartum maternal ICU admissions and several demographic and clinical risk factors, including preterm birth and abnormal placentation. Significance: What is Already Known on this Subject?: Severe maternal morbidity (SMM) is a key measure of maternity care quality. In recent years, as maternal mortality rates decline significantly in developed countries and due to its higher incidence, SMM has been suggested as a surrogate for quality assessment of maternity care evaluation. What this Study adds?: SMM rate appear to decrease during the study period, from 1.56 to 2013 to 1.12 per 1,000 in 2018. An independent association exists between peripartum maternal ICU admissions and several demographic and clinical risk factors: abnormal placentation (placenta previa or placenta accreta), preterm delivery (< 37 weeks), grand multiparity (≥ 5), history of recurrent pregnancy loss, and Jewish ethnicity (as opposed to Bedouin). These associations were independent of each other and additionally adjusted for several clinically relevant confounders.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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