Precise differentiation between jugular foramen paragangliomas and metastases: utility of diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging.
Purpose: This study tested the utility of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging (DCE-MRI) in differentiating paragangliomas and metastases in the jugular foramen in combination with conventional imaging. Methods: Forty-nine consecutive patients with paragangliomas or...
| Publicado en: | Neuroradiology Vol. 65; no. 4; pp. 805 - 814 |
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| Autores principales: | , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Apr2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=162642021&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 162642021 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Apr2023 vid: 65 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 162642021 161264065 162642021 162642021 10.1007/s00234-023-03113-0 162642021 ppf: 805 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Precise differentiation between jugular foramen paragangliomas and metastases: utility of diffusion-weighted and dynamic contrast-enhanced magnetic resonance imaging. aug: au: Ota, Yoshiaki Curaudeau, Guillaume Liao, Eric Bapuraj, Jayapalli Baba, Akira Shah, Gaurang Srinivasan, Ashok affil: Division of Neuroradiology, Department of Radiology, University of Michigan, 1500 E Medical Center Dr, UH B2, 48109, Ann Arbor, MI, USA sug: subj: Magnetic Resonance Imaging Methods Paraganglioma Diagnosis Neoplasm Metastasis Jugular Foramen Pathology Contrast Media Sensitivity and Specificity Human Male Female Adult Middle Age Aged Retrospective Design ROC Curve Descriptive Statistics Comparative Studies Lung Neoplasms Breast Neoplasms Melanoma Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Purpose: This study tested the utility of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging (DCE-MRI) in differentiating paragangliomas and metastases in the jugular foramen in combination with conventional imaging. Methods: Forty-nine consecutive patients with paragangliomas or metastases between January 2015 and April 2022 were included in this retrospective study. All patients had pretreatment DWI and DCE-MRI. Between paragangliomas and metastases, normalized apparent diffusion coefficient (nADCmean) and DCE-MRI parameters were compared along with conventional imaging features (enhancement pattern, presence of flow voids, cystic/necrotic change, and bone erosion). The diagnostic performance was tested using receiver operating characteristic (ROC) analysis. Results: Thirty-five paragangliomas (5 male; median 49 years) and 14 metastases (9 male; median 61 years) were analyzed. The most common 3 primary cancers included 4 lung cancers, 3 breast cancers, and 3 melanomas. The presence of flow void was significantly different between paragangliomas and metastases (21/35 vs 2/14; P = 0.0047) in conventional imaging features, while fractional plasma volume (Vp) was significantly different between the two tumor types (median 0.46 vs 0.19; P < 0.001) in DWI and DCE-MRI parameters. The areas under the ROC curves (AUCs) of the presence of flow void and Vp were 0.72 and 0.93, respectively. The AUC of the combination of the presence of flow void and Vp was 0.95 and significantly improved compared to that of the presence of flow void (P < 0.001). Conclusion: Adding DCE-MRI to the head and neck protocol can aid in the precise differentiation between jugular foramen paragangliomas and metastases. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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