بررسی عفونت هلیکوباکتر پیلوری در کودکان مبتال به دیس پپسی و پاسخ بالینی به درمان ریشه کنی هلیکوباکتر پیلوری و درمان دیس پپسی در این کودکان در شهر قم در سال های1397-98.
Background: The aim of this study was to evaluate the prevalence of helicobacter pylori (H. pylori) infection and its association with endoscopic, histopathological findings, and clinical symptoms of children with dyspepsia referring to Masoumeh Children Hospital of Qom. The eradication therapy of H...
| Publicado en: | Iranian Journal of Gastroenterology & Hepatology (GOVARESH) Vol. 27; no. 3; pp. 133 - 142 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Iranian Association of Gastroenterology & Hepatology
Autumn2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=162765209&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 162765209 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15607186 5DI0 jtl: Iranian Journal of Gastroenterology & Hepatology (GOVARESH) issn: 15607186 maglogo: N pubinfo: dt: Autumn2022 vid: 27 iid: 3 pid: 42050 pub: Iranian Association of Gastroenterology & Hepatology place: , <Blank> artinfo: ui: 162765209 162765209 162765209 162765209 ppf: 133 ppct: 9 formats: tig: atl: بررسی عفونت هلیکوباکتر پیلوری در کودکان مبتال به دیس پپسی و پاسخ بالینی به درمان ریشه کنی هلیکوباکتر پیلوری و درمان دیس پپسی در این کودکان در شهر قم در سال های1397-98. aug: au: حجت اله جعفری فشا ابوالفضل ایرانی ابوالفضل محمد بی محمد آزادگان سپیده قدری عنایت اله نوری affil: گروه اطفال، دانشکده پزشکی، مرکز آموزشی درمانی حضرت فاطمه معصومه )س(، دانشگاه علوم پزشکی قم، قم، ایران. sug: subj: Helicobacter Infections Epidemiology Dyspepsia Symptoms Helicobacter Pylori Disease Eradication Methods Hospitals, Pediatric Iran Human Male Female Child, Preschool Child Adolescence Iran Cross Sectional Studies Endoscopy, Gastrointestinal Methods Specimen Handling Pyloric Antrum Urease Analysis Histological Techniques Descriptive Statistics Comparative Studies Gastritis Signs and Symptoms, Digestive Prevalence Child, Preschool: 2-5 years Child: 6-12 years Adolescent: 13-18 years Male Female ab: Background: The aim of this study was to evaluate the prevalence of helicobacter pylori (H. pylori) infection and its association with endoscopic, histopathological findings, and clinical symptoms of children with dyspepsia referring to Masoumeh Children Hospital of Qom. The eradication therapy of H. pylori infection in children as well as the clinical response to dyspepsia in H. pylori-negative children, were evaluated. Materials and Methods: This cross-sectional study was performed on 170 children 4 to 15 years old with dyspepsia referred to Hazrat Masoumeh Hospital in Qom. After recording basic information about children such as age, sex, place of residence, and their disease history, these children were examined by endoscopy. Two biopsy specimens were obtained from the body and the antrum of the stomach. And if the rapid urease test and histology were positive for H. pylori tissue examination, the confirmed H. pylori infection would be considered in the child with H. pylori infection. Consequently, these patients were divided into two groups: H. pylori-positive and H. Pylori-negative. The two groups were compared for clinical signs and symptoms, endoscopic findings, and histological results. Results: 85 patients (49.4%) were male and 87 patients (50.6%) were female. No significant relationship was found between the sex of the patients, place of residence, and H. pylori infection. There was no significant difference between the two groups in gastritis erosive, duodenitis, gastritis erythematosus, esophagitis, and acute inflammation in the antrum. No mass was found in both groups, and no hemorrhagic gastritis, ulcer, duodenal metaplasia, dysplasia, maltoma, H. pylori accumulation, or atrophy was recorded. In H. pylori-positive subjects in 83 patients (95.4%), chronic inflammation in the antrum was mild and in four patients, it was moderate (4.6%). This finding in H. pylori-negative patients, in 31 patients (36.5%) was not found, and in 54 patients (63.5%) was found. There were no significant differences between the two groups in the clinical signs, abdominal pain, heartburn, anorexia, burning, recent weight loss, hematomas, melena, the only clinical symptom of nausea in HP positive patients (37.9%) and HP negative in 46 patients (54.1%) had a significant difference between the two groups. Nodular gastritis was found in the endoscopic evaluation of 27 (31%) patients with H. pylori infection, significantly more than dyspeptic patients (15 cases) who were H. pylori negative. Conclusion: According to the results of this study, no clinical signs other than nausea were correlated with H. pylori infection. In endoscopic findings, nodular gastritis has a significant correlation with H. pylori positivity, and according to the histopathological evaluation we significantly found more chronic gastritis in H. pylori infection. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: Persian refInfo: holdings: @attributes: islocal: N |
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