Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye–Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial.
(1) Background: The impairment of eye–hand coordination and smooth-pursuit eye movement caused by visual display terminal (VDT) operation is thought to impair daily living activities, for which no effective methods are currently known. On the other hand, various food ingredients, including astaxanth...
| Publicado en: | Nutrients Vol. 15; no. 6; pp. 1459 - 1471 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
MDPI
Mar2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=162814367&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 162814367 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20726643 B0TT jtl: Nutrients issn: 20726643 maglogo: N pubinfo: dt: Mar2023 vid: 15 iid: 6 pid: 97109 pub: MDPI artinfo: ui: 162814367 162814367 162814367 10.3390/nu15061459 162814367 ppf: 1459 ppct: 12 formats: tig: atl: Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye–Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial. aug: au: Yoshida, Keisuke Sakai, Osamu Honda, Tomoo Kikuya, Tomio Takeda, Ryuji Sawabe, Akiyoshi Inaba, Masamaru Koike, Chieko affil: Senju Pharmaceutical, Co., Ltd., Osaka 541-0048, Japan sug: subj: Vision Disorders Surgery Eye Surgery Adverse Effects Dietary Supplementation Xanthophylls Pharmacodynamics Lutein Pharmacodynamics Zeaxanthin Pharmacodynamics Eye Movements Drug Effects Hand Drug Effects Human Funding Source Randomized Controlled Trials Random Assignment Double-Blind Studies Eye Diseases Prevention and Control ab: (1) Background: The impairment of eye–hand coordination and smooth-pursuit eye movement caused by visual display terminal (VDT) operation is thought to impair daily living activities, for which no effective methods are currently known. On the other hand, various food ingredients, including astaxanthin, lutein, and zeaxanthin, are known to help improve the eye health of VDT operators. This study aimed to test the hypothesis that the combination of astaxanthin, lutein, and zeaxanthin can prevent the impairment of eye–hand coordination and smooth-pursuit eye movement caused by VDT operation. (2) Methods: We conducted a randomized, placebo-controlled, parallel-group clinical trial. Healthy subjects who regularly worked with VDTs were randomly assigned to the active and placebo groups. All of the subjects took soft capsules containing 6 mg of astaxanthin, 10 mg of lutein, and 2 mg of zeaxanthin or placebo soft capsules once daily for eight weeks. We evaluated the eye–hand coordination, smooth-pursuit eye movements, and macular pigment optical density (MPOD) at 0, two, four, and eight weeks after soft-capsule intake. (3) Results: The active group showed significantly improved eye–hand coordination after VDT operation at eight weeks. However, there was no clear improvement in the effect of the supplementation on smooth-pursuit eye movements. The active group also showed a significant increase in MPOD levels. (4) Conclusions: Consumption of a supplement containing astaxanthin, lutein, and zeaxanthin mitigates the decline of eye–hand coordination after VDT operation. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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