Use of Swedish smokeless tobacco during pregnancy: A systematic review of pregnancy and early life health risk.

Background and Aims: Smokeless tobacco is a heterogeneous product group with diverse composition and prevalence globally. Tobacco use during pregnancy is concerning due to the risk of adverse pregnancy outcomes and effects on child health. Nicotine may mediate several of these effects. This systemat...

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Publicado en:Addiction Vol. 118; no. 5; pp. 789 - 804
Autores principales: Brinchmann, Bendik C., Vist, Gunn E., Becher, Rune, Grimsrud, Tom K., Elvsaas, Ida‐Kristin Ørjasæter, Underland, Vigdis, Holme, Jørn A., Carlsen, Karin C. Lødrup, Kreyberg, Ina, Nordhagen, Live S., Bains, Karen Eline Stensby, Carlsen, Kai‐Håkon, Alexander, Jan, Valen, Håkon
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell May2023
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Use of Swedish smokeless tobacco during pregnancy: A systematic review of pregnancy and early life health risk.
      aug:
        au:
          Brinchmann, Bendik C.
          Vist, Gunn E.
          Becher, Rune
          Grimsrud, Tom K.
          Elvsaas, Ida‐Kristin Ørjasæter
          Underland, Vigdis
          Holme, Jørn A.
          Carlsen, Karin C. Lødrup
          Kreyberg, Ina
          Nordhagen, Live S.
          Bains, Karen Eline Stensby
          Carlsen, Kai‐Håkon
          Alexander, Jan
          Valen, Håkon
        affil: Division of Climate and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway
      sug:
        subj:
          Tobacco, Smokeless Utilization
          Tobacco Products Adverse Effects
          Pregnancy Outcomes
          Substance Abuse, Perinatal Complications
          Human
          Pregnancy
          Female
          Fetus
          Infant, Newborn
          Systematic Review
          Meta Analysis
          Descriptive Statistics
          Confidence Intervals
          Odds Ratio
          Uncertainty
          Child Health
          Prenatal Exposure Delayed Effects
          Medline
          Embase
          Psycinfo
          Cochrane Library
          Infant Mortality Risk Factors
          Fetus, conception to birth
          Infant, Newborn: birth-1 month
          Female
      ab: Background and Aims: Smokeless tobacco is a heterogeneous product group with diverse composition and prevalence globally. Tobacco use during pregnancy is concerning due to the risk of adverse pregnancy outcomes and effects on child health. Nicotine may mediate several of these effects. This systematic review measured health outcomes from Swedish smokeless tobacco (snus) use during pregnancy. Method: Literature search was conducted by an information specialist in May 2022. We included human studies of snus use during pregnancy compared with no tobacco use, assessed risk of bias, conducted a meta‐analysis and assessed confidence in effect‐estimates using Grading of Recommendations, Assessment, Development and Evaluations (GRADE). Results: We included 18 cohort studies (42 to 1 006 398 participants). Snus use during pregnancy probably (moderate confidence in risk estimates) increase the risk of neonatal apnea, adjusted odds ratio 95% confidence interval [aOR (95% CI)] 1.96 (1.30 to 2.96). Snus use during pregnancy possibly (low confidence in risk estimates) increase the risk of stillbirths aOR 1.43 (1.02 to 1.99), extremely premature births aOR 1.69 (1.17 to 2.45), moderately premature birth aOR 1.26 (1.15 to 1.38), SGA aOR 1.26 (1.09 to 1.46), reduced birth weight mean difference of 72.47 g (110.58 g to 34.35 g reduction) and oral cleft malformations aOR 1.48 (1.00 to 2.21). It is uncertain (low confidence in risk estimates, CI crossing 1) whether snus use during pregnancy affects risk of preeclampsia aOR 1.11 (0.97 to 1.28), antenatal bleeding aOR 1.15 (0.92 to 1.44) and very premature birth aOR 1.26 (0.95 to 1.66). Risk of early neonatal mortality and altered heart rate variability is uncertain, very low confidence. Snus using mothers had increased prevalence of caesarean sections, low confidence. Conclusions: This systematic review reveals that use of smokeless tobacco (snus) during pregnancy may adversely impact the developing child.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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