Tree-Based Risk Factor Identification and Stroke Level Prediction in Stroke Cohort Study.

Objective. This study focuses on the identification of risk factors, classification of stroke level, and evaluation of the importance and interactions of various patient characteristics using cohort data from the Second Hospital of Lanzhou University. Methodology. Risk factors are identified by eval...

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Publicado en:BioMed Research International pp. 1 - 11
Autores principales: Li, Junyao, Luo, Yuxiang, Dong, Meina, Liang, Yating, Zhao, Xuejing, Zhang, Yafeng, Ge, Zhaoming
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 4/10/2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 4/10/2023
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2023/7352191
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        atl: Tree-Based Risk Factor Identification and Stroke Level Prediction in Stroke Cohort Study.
      aug:
        au:
          Li, Junyao
          Luo, Yuxiang
          Dong, Meina
          Liang, Yating
          Zhao, Xuejing
          Zhang, Yafeng
          Ge, Zhaoming
        affil: School of Mathematics and Statistics, Center for Data Science, Lanzhou University, Lanzhou, 730000, China
      sug:
        subj:
          Risk Assessment
          Stroke Risk Factors
          Stroke Classification
          Disease Attributes
          Human
          China
          Hospitals
          Hypertension
          Stroke Diagnosis
          Age Factors
          Sex Factors
          Cerebral Ischemia, Transient
          Family History
          Funding Source
          Obesity
          Hyperlipidemia
          Smoking
          Prospective Studies
      ab: Objective. This study focuses on the identification of risk factors, classification of stroke level, and evaluation of the importance and interactions of various patient characteristics using cohort data from the Second Hospital of Lanzhou University. Methodology. Risk factors are identified by evaluation of the relationships between factors and response, as well as by ranking the importance of characteristics. Then, after discarding negligible factors, some well-known multicategorical classification algorithms are used to predict the level of stroke. In addition, using the Shapley additive explanation method (SHAP), factors with positive and negative effects are identified, and some important interactions for classifying the level of stroke are proposed. A waterfall plot for a specific patient is presented and used to determine the risk degree of that patient. Results and Conclusion. The results show that (1) the most important risk factors for stroke are hypertension, history of transient ischemia, and history of stroke; age and gender have a negligible impact. (2) The XGBoost model shows the best performance in predicting stroke risk; it also gives a ranking of risk factors based on their impact. (3) A combination of SHAP and XGBoost can be used to identify positive and negative factors and their interactions in stroke prediction, thereby providing helpful guidance for diagnosis.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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