Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.

Background: Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies. Oxidative stress has been validated as a critical event involved in DOX-induced neurotoxicity. As a selective autophagy adaptor protein, p62 is reported to regulate Keap1-Nrf2-ARE antioxidant pathway in respo...

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Bibliographic Details
Published in:Psychopharmacology Vol. 240; no. 5; pp. 1179 - 1191
Main Authors: Liao, Dehua, Shangguan, Danggang, Wu, Yi, Chen, Yun, Liu, Ni, Tang, Jingyi, Yao, Dunwu, Shi, Yingrui
Format: Journal Article
Published: Springer Nature May2023
Online Access:View this record in EBSCOhost