Association between the NEP rs701109 polymorphism and the clinical efficacy and safety of sacubitril/valsartan in Chinese patients with heart failure.

Objective: Sacubitril/valsartan is a commonly used medicine for treating heart failure (HF) patients, but the treatment effects significantly vary. Neprilysin (NEP) and carboxylesterase 1 (CES1) play an important role in the efficacy of sacubitril/valsartan. The purpose of this study was to explore...

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Publicado en:European Journal of Clinical Pharmacology Vol. 79; no. 5; pp. 663 - 671
Autores principales: Luo, Hong-Yu, Gao, Li-Chen, Long, Hui-Zhi, Zhou, Zi-Wei, Xu, Shuo-Guo, Li, Feng-Jiao, Li, Hong-Li, Cheng, Yan, Li, Cai-Xia, Peng, Xing-Yu, Li, Liang, Chen, Ran, Deng, Ping
Formato: research tables/charts Journal Article
Publicado: Springer Nature May2023
Acceso en línea:Ver este registro en EBSCOhost