Intrinsic Structural Connectivity of the Default Mode Network and Behavioral Correlates of Executive Function and Social Skills in Youth with Autism Spectrum Disorders.
Brain connectivity of individuals with autism spectrum disorders (ASD) is heterogenous, as are the behavioral manifestations. The current study investigated brain-behavior relationships in the context of social skills and executive function profiles with data from the Autism Brain Imaging Database E...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 53; no. 5; pp. 1930 - 1942 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=163252955&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 163252955 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: May2023 vid: 53 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 163252955 155159855 163252955 163252955 10.1007/s10803-022-05460-y 163252955 ppf: 1930 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Intrinsic Structural Connectivity of the Default Mode Network and Behavioral Correlates of Executive Function and Social Skills in Youth with Autism Spectrum Disorders. aug: au: Blume, Jessica Kahathuduwa, Chanaka Mastergeorge, Ann affil: Department of Human Development and Family Sciences, Texas Tech University, P.O. Box 41230, 79409-1230, Lubbock, TX, USA sug: subj: Executive Function Social Skills Autism Spectrum Disorder Social Behavior Human Magnetic Resonance Imaging Structural Equation Modeling Factor Analysis Scales Funding Source ab: Brain connectivity of individuals with autism spectrum disorders (ASD) is heterogenous, as are the behavioral manifestations. The current study investigated brain-behavior relationships in the context of social skills and executive function profiles with data from the Autism Brain Imaging Database Exchange II. We calculated connectivity measures from diffusion tensor imaging using Bayesian estimation and probabilistic tractography. Subsequently, we performed structural equation modeling by regressing three latent factors, yielded from an exploratory factor analysis, onto total default mode network (DMN) connectivity. Both social regulation processing and self-directed cognitive processing factors moderately, negatively correlated with total DMN connectivity. Our findings indicate social regulation processing difficulties in youth with ASD may be attributable to impaired connectivity between the anterior and posterior DMN. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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