Associations Between Children's Telomere Length, Parental Intrusiveness, and the Development of Early Externalizing Behaviors.

Shorter telomeres mark cellular aging and are linked to chronic stress exposure as well as negative physical and psychological outcomes. However, it is unclear whether telomere length mediates associations between early stress exposure and later externalizing problems, or whether boys and girls diff...

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Published in:Child Psychiatry & Human Development Vol. 54; no. 3; pp. 672 - 683
Main Authors: Daoust, Andrew R., Thakur, Aditi, Kotelnikova, Yuliya, Kleiber, Morgan L., Singh, Shiva M., Hayden, Elizabeth P.
Format: Article
Published: Springer Nature Jun2023
Subjects:
Online Access:View this record in EBSCOhost
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      dt: Jun2023
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      pub: Springer Nature
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        10.1007/s10578-021-01279-3
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        atl: Associations Between Children's Telomere Length, Parental Intrusiveness, and the Development of Early Externalizing Behaviors.
      aug:
        au:
          Daoust, Andrew R.
          Thakur, Aditi
          Kotelnikova, Yuliya
          Kleiber, Morgan L.
          Singh, Shiva M.
          Hayden, Elizabeth P.
        affil:
          Department of Psychology, University of Western Ontario, London, ON, Canada
          Department of Psychology, Brain and Mind Institute, Western University, Western Interdisciplinary Research Building, Room 2178, Perth Drive, N6A 5B7, London, ON, Canada
          Department of Biology, University of Western Ontario, London, ON, Canada
          Department of Psychology, University of Notre Dame, Notre Dame, IN, USA
      su:
        Externalizing behavior
        Birthparents
        Sex (Biology)
        Telomeres
        Cellular aging
      sug:
        subj:
          Externalizing behavior
          Birthparents
          Sex (Biology)
          Telomeres
          Cellular aging
      keyword:
        Developmental
        Externalizing symptoms
        Parental intrusiveness
        Sex differences
        Telomere length
        Developmental
        Externalizing symptoms
        Parental intrusiveness
        Sex differences
        Telomere length
      ab: Shorter telomeres mark cellular aging and are linked to chronic stress exposure as well as negative physical and psychological outcomes. However, it is unclear whether telomere length mediates associations between early stress exposure and later externalizing problems, or whether boys and girls differ in pathways to these concerns. We therefore examined associations between telomere length, early stress via negative caregiving, and children's externalizing symptom development over time in 409 three-year-old children and their parents. Telomere length mediated the association between early parental intrusiveness and later rule-breaking behavior; however, this association was moderated by children's biological sex such that parent intrusiveness was related only to boys' rule-breaking. Findings support the notion that children's telomere length may mark individual differences in responses to negative early caregiving, and highlight a potential mechanism contributing to the development of rule-breaking problems in boys.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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