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What Should Be the Surgical Technique for Treating Thin Melanoma?

Surgical techniques with complete margin assessment (e.g., Mohs surgery, staged excision with permanent sections) allow pathologic examination of the entire marginal surface of a cancer excision specimen. Compared with conventional wide excision, complete margin assessment may reduce sampling error...

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Published in:NEJM Evidence Vol. 2; no. 5; pp. 1 - 5
Main Authors: Yu, Wesley Y., Bordeaux, Jeremy S.
Format: review Journal Article
Published: MMS Publications May2023
Online Access:View this record in EBSCOhost
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      dt: May2023
      vid: 2
      iid: 5
      pid: 1373
      pub: MMS Publications
      place: Waltham, Massachusetts
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        10.1056/EVIDtt2200321
        163445445
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        atl: What Should Be the Surgical Technique for Treating Thin Melanoma?
      aug:
        au:
          Yu, Wesley Y.
          Bordeaux, Jeremy S.
        affil: Department of Dermatology, Oregon Health & Science University, Portland, OR
      sug:
        subj:
          Melanoma Surgery
          Surgical Site
          Sampling Error
          Surgical Margin
      ab: Surgical techniques with complete margin assessment (e.g., Mohs surgery, staged excision with permanent sections) allow pathologic examination of the entire marginal surface of a cancer excision specimen. Compared with conventional wide excision, complete margin assessment may reduce sampling error when evaluating margin status, allow for more rapid surgical clearance of positive margins, and minimize surgical defect size in anatomically constrained locations (e.g., face, hands, feet, genitals). Prospective data comparing the safety and efficacy of complete margin assessment and conventional wide excision in the treatment of melanoma are lacking. This article reviews the evidence and proposes a trial to address the question: Which is the better surgical method for treating thin invasive melanoma and melanoma in situ in high-risk anatomical locations?
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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