Hypogammaglobulinemia in pediatric kidney transplant recipients.

Infections remain the most common cause of hospitalization after kidney transplantation, contributing to significant post-transplant morbidity and mortality. There is a growing body of literature that suggests that immunoglobulins may have a significant protective role against post-transplant infect...

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Publicado en:Pediatric Nephrology Vol. 38; no. 6; pp. 1753 - 1763
Autores principales: Dimitriades, Victoria, Butani, Lavjay
Formato: exam questions review tables/charts Journal Article
Publicado: Springer Nature Jun2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2023
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      pub: Springer Nature
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        atl: Hypogammaglobulinemia in pediatric kidney transplant recipients.
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        au:
          Dimitriades, Victoria
          Butani, Lavjay
        affil: Division of Pediatric Allergy, Immunology and Rheumatology, Department of Pediatrics, University of California, Davis, Sacramento, CA, USA
      sug:
        subj:
          Agammaglobulinemia Epidemiology
          Agammaglobulinemia Etiology
          Kidney Transplantation In Infancy and Childhood
          Transplant Recipients In Infancy and Childhood
          Postoperative Complications
          Cross Infection Prevention and Control
          Immunoglobulins Therapeutic Use
          Child
          Treatment Outcomes
          Nephrologists
          Morbidity Risk Factors
          Mortality Risk Factors
          Child: 6-12 years
      ab: Infections remain the most common cause of hospitalization after kidney transplantation, contributing to significant post-transplant morbidity and mortality. There is a growing body of literature that suggests that immunoglobulins may have a significant protective role against post-transplant infections, although the literature remains sparse, inconsistent, and not well publicized among pediatric nephrologists. Of great concern are data indicating a high prevalence of immunoglobulin abnormalities following transplantation and a possible link between these abnormalities and poorer outcomes. Our educational review focuses on the epidemiology and risk factors for the development of immunoglobulin abnormalities after kidney transplantation, the outcomes in patients with low immunoglobulin levels, and studies evaluating possible interventions to correct these immunoglobulin abnormalities.
      pubtype: Academic Journal
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    language: English
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