Top-Down and Bottom-Up Contributions to Memory Performance in OCD: A Multilevel Meta-Analysis With Clinical Implications.

Despite extensive coverage of a relationship between memory performance and executive function in the obsessive-compulsive disorder (OCD) literature, the relative contributions of specific aspects of executive control have remained elusive. We, therefore, extend our previous multilevel meta-analysis...

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Publicado en:Journal of Psychopathology & Clinical Science Vol. 132; no. 4; pp. 428 - 445
Autores principales: Harkin, Ben, Persson, Sofia, Yates, Alan, Jauregi, Ainara, Kessler, Klaus
Formato: Artículo
Publicado: American Psychological Association May2023
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2023
      vid: 132
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      pub: American Psychological Association
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        10.1037/abn0000793
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        atl: Top-Down and Bottom-Up Contributions to Memory Performance in OCD: A Multilevel Meta-Analysis With Clinical Implications.
      aug:
        au:
          Harkin, Ben
          Persson, Sofia
          Yates, Alan
          Jauregi, Ainara
          Kessler, Klaus
        affil:
          Department of Psychology, Manchester Metropolitan University
          School of Social Sciences, Leeds Beckett University
          Aston Institute of Health and Neurodevelopment, Aston University
          School of Psychology, University College Dublin
      su:
        Obsessive-compulsive disorder
        Executive function
        Control (Psychology)
        Sensory memory
        Memory disorders
        Group psychoanalysis
      sug:
        subj:
          Obsessive-compulsive disorder
          Executive function
          Control (Psychology)
          Sensory memory
          Memory disorders
          Group psychoanalysis
      keyword:
        bottom-up
        executive function
        memory
        OCD
        top-down
        bottom-up
        executive function
        memory
        OCD
        top-down
      ab: Despite extensive coverage of a relationship between memory performance and executive function in the obsessive-compulsive disorder (OCD) literature, the relative contributions of specific aspects of executive control have remained elusive. We, therefore, extend our previous multilevel meta-analysis (Persson et al., 2021), where demand on executive function was the most significant determinant of memory deficits in OCD, and provide a finer-grained analysis of executive control via a segregation into top-down (attentional control, maintenance and updating, planning) and bottom-up (perceptual integration, perceptual salience) contributions. Our multilevel meta-analytic approach allowed us to accommodate the interdependency of 255 effect sizes from 131 studies, totaling 4,101 OCD patients. Results revealed that maintenance and updating (top-down) and perceptual integration (bottom-up) predicted memory performance generally, and specifically in those with clinical OCD. Exploratory analyses suggested that this effect may be somewhat different among subclinical OCD groups; however, these findings should be considered with conceptual and analytical caveats in mind. We explain these results via deficient sensory (perceptual integration) and working memory (maintenance and updating) gating mechanisms and propose a model to accommodate their expression in OC symptoms. In conclusion, our meta-analysis has expanded understanding of cognitive performance in OCD and identifies the possibility of untapped cognitive targets for intervention. General Scientific Summary: Deficits in executive function and memory are common in OCD. We identify and test two novel frameworks, top-down and bottom-up, to explain memory deficits in OCD using a multilevel meta-analysis. We found that maintenance and updating, as well as perceptual integration, predicted memory deficits in OCD, where in turn we explained these via deficient sensory and working memory (WM) gating mechanisms, respectively. Our meta-analytical results and explanations may inform future novel interventions.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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