Directional associations between cannabis use and depression from late adolescence to young adulthood: the role of adverse childhood experiences.

Background and aims: Although the co‐occurrence of cannabis and depression is well established, less is known about the temporal sequence of cannabis use and depression. The present study had three main aims: to test a symptom‐driven pathway in which depression may drive increases in cannabis use, t...

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Publicado en:Addiction Vol. 118; no. 6; pp. 1083 - 1093
Autores principales: Davis, Jordan P., Pedersen, Eric R., Tucker, Joan S., Prindle, John, Dunbar, Michael S., Rodriguez, Anthony, Seelam, Rachana, D'Amico, Elizabeth J.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Jun2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2023
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      pub: Wiley-Blackwell
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        atl: Directional associations between cannabis use and depression from late adolescence to young adulthood: the role of adverse childhood experiences.
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          Davis, Jordan P.
          Pedersen, Eric R.
          Tucker, Joan S.
          Prindle, John
          Dunbar, Michael S.
          Rodriguez, Anthony
          Seelam, Rachana
          D'Amico, Elizabeth J.
        affil: Suzanne Dworak‐Peck School of Social Work, University of Southern California, Los Angeles CA,, USA
      sug:
        subj:
          Cannabis
          Substance Use Disorders In Adolescence
          Substance Use Disorders In Adulthood
          Depression In Adolescence
          Depression In Adulthood
          Adverse Childhood Experiences
          Human
          Funding Source
          United States
          Prospective Studies
          Male
          Female
          Adolescence
          Young Adult
          Questionnaires
          Scales
          Adolescent: 13-18 years
          Male
          Female
      ab: Background and aims: Although the co‐occurrence of cannabis and depression is well established, less is known about the temporal sequence of cannabis use and depression. The present study had three main aims: to test a symptom‐driven pathway in which depression may drive increases in cannabis use, to test a substance‐induced pathway in which cannabis use may drive increases in depression and to assess a shared vulnerability model assessing associations between individuals who have (and have not) experienced adverse childhood experiences (ACEs). Design: Data are from an ongoing, longitudinal, cohort study (n = 2234). Data were set up in an accelerated longitudinal design from age 17 to 24 years. Setting: Initial sample was recruited from Southern California, USA. The majority of participants still live in Southern California. Participants: On average, participants were aged 18 years at wave 8, with more than half identifying as female (54.3%; n = 1350). Most participants identified as Hispanic (1127; 45.4%), followed by non‐Hispanic white (510; 20.5%), Asian (503; 20.2%), multi‐racial/other (284; 11.4%) and non‐Hispanic black (60; 2.2%). Measurements Primary outcomes were past‐month days of cannabis use and depression symptoms [patient health questionnaire (PHQ)‐8]. The Adverse Childhood Experiences scale was used as our main grouping measure. Findings In the full sample, we showed that prior levels of depression symptoms were associated with a decrease in cannabis use [opposite to the proposed symptom driven model; B = −0.33 (−0.58, −0.09)]. Dynamic coupling parameters noted individuals who evidenced greater increases in cannabis use between two prior ages reported greater increases in depressive symptoms between subsequent ages [support for a substance‐induced pathway; B = 0.53 (0.18, 0.89)]. Similar to the overall sample, for those who had not experienced ACEs, as cannabis use increased we saw a steady increase in depression [support for a substance induced pathway; B = 0.14 (0.04, 0.29)]. However, for those who experienced ACEs, as cannabis use increased we saw a consistent decrease in depression [opposite to the proposed substance‐induced pathway; B = −0.18 (−0.28, −0.08)]. Conclusion: There is mixed support for both symptom‐driven and substance‐induced pathways between cannabis use and depression.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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