A Rapid, Shallow Whole Genome Sequencing Workflow Applicable to Limiting Amounts of Cell-Free DNA.

BACKGROUND: Somatic copy number alterations (sCNAs) acquired during the evolution of breast cancer provide valuable prognostic and therapeutic information. Here we present a workflow for screening sCNAs using picogram amounts of cell-free DNA (cfDNA) and single circulating tumor cells (CTCs). METHOD...

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Detalles Bibliográficos
Publicado en:Clinical Chemistry Vol. 69; no. 5; pp. 510 - 519
Autores principales: Allsopp, Rebecca C., Page, Karen, Ambasager, Bana, Wadsley, Marc K., Acheampong, Emmanuel, Ntereke, Tumisang P., Qi Guo, Lall, Gurdeep Matharu, Gleason, Kelly L. T., Wren, Evie, Nteliopoulos, Georgios, Rushton, Amelia J., Coombes, R. Charles, Shaw, Jacqueline A.
Formato: Journal Article
Publicado: Oxford University Press / USA May2023
Acceso en línea:Ver este registro en EBSCOhost