High Interest in Long-acting Injectable Pre-exposure Prophylaxis (LAI-PrEP) for HIV Prevention Among Men Who Have Sex With Men (MSM): Result From A Nationwide Survey in Malaysia.
The recent approval of long-acting injectable cabotegravir (CAB-LA) as PrEP for HIV prevention could be an attractive alternative for MSM, particularly among those who face barriers to adherence using the oral pill. This study reports on the awareness of long-acting injectable PrEP (LAI-PrEP) and fa...
| Published in: | Journal of Community Health Vol. 48; no. 3; pp. 513 - 522 |
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| Main Authors: | , , , , , , , |
| Format: | Article |
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Springer Nature
Jun2023
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| Subjects: | |
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=163827794&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 163827794 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00945145 JCH jtl: Journal of Community Health issn: 00945145 maglogo: N pubinfo: dt: Jun2023 vid: 48 iid: 3 pid: 237 pub: Springer Nature artinfo: ui: 163827794 10.1007/s10900-023-01195-8 ppf: 513 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P size: 1.2MB tig: atl: High Interest in Long-acting Injectable Pre-exposure Prophylaxis (LAI-PrEP) for HIV Prevention Among Men Who Have Sex With Men (MSM): Result From A Nationwide Survey in Malaysia. aug: au: Paudel, Kiran Gupta, Sana Gautam, Kamal Wickersham, Jeffrey A Khati, Antoine Azwa, Iskandar Ha, Toan Shrestha, Roman affil: Nepal Health Frontiers, Tokha-5, Kathmandu, Nepal Department of Allied Health Sciences, University of Connecticut, 06269, Storrs, CT, USA Yale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, 135 College St., Suite 323, 06510, New Haven, CT, USA Centre of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Infectious Diseases Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Department of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 15261, Pittsburgh, PA, USA 358 Mansfield Road, 1101, 06260-1101, Unit, Storrs, CT, USA su: Malaysia Facebook (Web resource) Health services accessibility Cross-sectional method Social media Medical care costs Men who have sex with men HIV prevention HIV infections Injections Confidence intervals Middle-income countries Pre-exposure prophylaxis Surveys Controlled release preparations Low-income countries Descriptive statistics Research funding Statistical sampling Odds ratio Data analysis software sug: subj: Health services accessibility Cross-sectional method Social media Medical care costs Men who have sex with men Malaysia Marketing Research and Public Opinion Polling HIV prevention HIV infections Injections Confidence intervals Middle-income countries Pre-exposure prophylaxis Surveys Controlled release preparations Low-income countries Descriptive statistics Research funding Statistical sampling Odds ratio Data analysis software Facebook (Web resource) keyword: cabotegravir HIV long-acting injectable PrEP (LAI-PrEP) men who have sex with men (MSM) Pre-exposure prophylaxis (PrEP) cabotegravir HIV long-acting injectable PrEP (LAI-PrEP) men who have sex with men (MSM) Pre-exposure prophylaxis (PrEP) ab: The recent approval of long-acting injectable cabotegravir (CAB-LA) as PrEP for HIV prevention could be an attractive alternative for MSM, particularly among those who face barriers to adherence using the oral pill. This study reports on the awareness of long-acting injectable PrEP (LAI-PrEP) and factors associated with interest in LAI-PrEP use among a nationwide sample of MSM in Malaysia. An online cross-sectional survey was conducted between August and September 2021 to explore perspectives on PrEP modalities among Malaysian MSM (N = 870). Convenience sampling was used to recruit participants using ads on two platforms hornet and facebook. While only 9.1% of the study participants were aware of LAI-PrEP, the majority had heard of oral PrEP (80.9%). After giving a description of it, a large majority (86.6%) expressed interest in using it if made accessible. Those who had a prior history of HIV testing (aOR = 1.9; 95% CI = 1.2–3.2) were more likely to use LAI-PrEP. Interestingly, despite the concerns related to potential high cost (aOR = 3.4; 95% CI = 2.1–5.5) and long-term side effects (aOR = 1.9; 95% CI = 1.2–3.1), the majority of the participants were interested in using LAI-PrEP. Those who were afraid of (or disliked) syringes were less interested in using it (aOR = 0.2; 95% CI; 0.1–0.4). In the recent context that LAI-PrEP was shown to be safe and effective at preventing HIV, our results indicate its potential relevance as an additional PrEP option that could accelerate the uptake and scale-up of PrEP. However, it is crucial to conduct future research urgently to improve the understanding of strategies that could enhance the accessibility, acceptability, and affordability of LAI-PrEP for MSM in low- and middle-income countries, including Malaysia. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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