Atypical monkeypox presentation in a previously vaccinated MSM HIV-positive adult.
The outbreak of monkeypox virus (MPXV) in non-endemic countries is an international public health emergency, and the diversity in manifestations poses challenges for early diagnosis and isolation. We describe an atypical case of monkeypox (MPX) in a 46-year-old homosexual male living with HIV. He re...
| Published in: | Infection Vol. 51; no. 3; pp. 783 - 787 |
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| Main Authors: | , , , , , , , , , |
| Format: | case study pictorial Journal Article |
| Published: |
Springer Nature
Jun2023
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=163870491&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 163870491 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03008126 NXO jtl: Infection issn: 03008126 maglogo: N pubinfo: dt: Jun2023 vid: 51 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 163870491 161270520 163870491 163870491 10.1007/s15010-022-01967-9 163870491 ppf: 783 ppct: 4 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Atypical monkeypox presentation in a previously vaccinated MSM HIV-positive adult. aug: au: Crosato, Verena Degli Antoni, Melania Izzo, Ilaria Cerini, Carlo Pennati, Francesca Gulletta, Maurizio Odolini, Silvia Tomasoni, Lina Rachele Matteelli, Alberto Castelli, Francesco affil: Unit of Infectious and Tropical Diseases, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy sug: subj: Monkeypox Diagnosis Poxvirus Infections Prevention and Control Men Who Have Sex With Men HIV-Positive Persons HIV Infections Drug Therapy Disease Outbreaks Prevention and Control Public Health Skin Ulcer Vaccination Coverage Sexual and Gender Minorities Middle Age Male Early Diagnosis Social Isolation Gay Men Fever Symptoms Biopsy Pyoderma Gangrenosum Superinfection Patient Discharge Skin Manifestations Vaccination Status Adult Middle Aged: 45-64 years Adult: 19-44 years Male ab: The outbreak of monkeypox virus (MPXV) in non-endemic countries is an international public health emergency, and the diversity in manifestations poses challenges for early diagnosis and isolation. We describe an atypical case of monkeypox (MPX) in a 46-year-old homosexual male living with HIV. He reported 1-day duration fever, a lesion on his chin that, over a period of 18 days, had gradually enlarged and ulcerated. Biopsy examination performed at an external centre revealed pyoderma gangrenosum, unconfirmed at a subsequent biopsy. When he reported to our hospital outpatients' clinic the chin lesion had a diameter of 5 × 5 cm, necrotic margins and ulcerated base and signs of superinfection. He was admitted for further investigations. Three swabs collected from pharynx, skin and chin lesion resulted positive for MPXV. He had a favourable clinical course and was discharged soon after. Pending the achievement of optimal vaccination coverage in at-risk groups, early identification and isolation of infectious patients represent the cornerstones of the containment strategy. Atypical cases of MPX manifestations are not uncommon, particularly in patients with HIV infection. A high level of suspicion should be maintained to identify infectious cases at an early stage and avoid further spread of the infection. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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