Narrative recall in relapsing-remitting multiple sclerosis: A potentially useful speech task for detecting subtle cognitive changes.

Our research studied relapsing-remitting multiple sclerosis (RRMS). In half of the RRMS cases, mild cognitive difficulties are present, but often remain undetected despite their adverse effects on individuals' daily life. Detecting subtle cognitive alterations using speech analysis have rarely been...

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Publicado en:Clinical Linguistics & Phonetics Vol. 37; no. 4-6; pp. 549 - 567
Autores principales: Svindt, Veronika, Gosztolya, Gábor, Gráczi, Tekla E.
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2023
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
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        10.1080/02699206.2023.2170830
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        atl: Narrative recall in relapsing-remitting multiple sclerosis: A potentially useful speech task for detecting subtle cognitive changes.
      aug:
        au:
          Svindt, Veronika
          Gosztolya, Gábor
          Gráczi, Tekla E.
        affil: Research Centre for Linguistics, Eötvös Loránd Research Network, Budapest, Hungary
      sug:
        subj:
          Cognition Disorders Diagnosis
          Narratives
          Recurrence
          Speech Perception
          Task Performance and Analysis
          Memory
          Multiple Sclerosis
          Human
          Voice Recognition Systems
          Skill Acquisition
          Psychomotor Performance
          Speech and Language Assessment
          Speech Rate
          Descriptive Statistics
          ROC Curve
          Sensitivity and Specificity
          Cognition
          One-Way Analysis of Variance
          Chi Square Test
          Questionnaires
          Hungary
          Adult
          Middle Age
          Male
          Female
          Neuropsychological Tests
          Multiple Linear Regression
          Executive Function
          Memory, Short Term
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Our research studied relapsing-remitting multiple sclerosis (RRMS). In half of the RRMS cases, mild cognitive difficulties are present, but often remain undetected despite their adverse effects on individuals' daily life. Detecting subtle cognitive alterations using speech analysis have rarely been implemented in MS research. We applied automatic speech recognition technology to devise a speech task with potential diagnostic value. Therefore, we used two narrative tasks adjusted for the neural and cognitive characteristics of RRMS; namely narrative recall and personal narrative. In addition to speech analysis, we examined the information processing speed, working memory, verbal fluency, and naming skills. Twenty-one participants with RRMS and 21 gender-, age-, and education-matched healthy controls took part in the study. All the participants with RRMS achieved a normal performance on Addenbrooke's Cognitive Examination. The following parameters of speech were measured: articulation and speech rate, the proportion, duration, frequency, and average length of silent and filled pauses. We found significant differences in the temporal parameters between groups and speech tasks. ROC analysis produced high classification accuracy for the narrative recall task (0.877 and 0.866), but low accuracy for the personal narrative task (0.617 and 0.592). The information processing speed affected the speech of the RRMS group but not that of the control group. The higher cognitive load of the narrative recall task may be the cause of significant changes in the speech of the RRMS group relative to the controls. Results suggest that narrative recall task may be effective for detecting subtle cognitive changes in RRMS.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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