Effect of silicone oil on retinal microcirculation after vitrectomy for rhegmatogenous retinal detachment evaluated by OCT angiography: a literature review.

Silicone oil (SO) has been widely used as intravitreal tamponade agent for rhegmatogenous retinal detachment (RRD) and has been occasionally associated with incomplete retinal structural and functional recovery. The use of Optical Coherence Tomography Angiography (OCT-A) has recently attracted signi...

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Publicado en:Therapeutic Advances in Ophthalmology pp. 1 - 14
Autores principales: Christou, Evita Evangelia, Papaconstantinou, Dimitrios, Droutsas, Konstantinos, Stefaniotou, Maria, Stavrakas, Panagiotis, Kandarakis, Stylianos, Petrou, Petros, Georgalas, Ilias
Formato: review tables/charts Journal Article
Publicado: Sage Publications Inc. 5/24/2023
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Effect of silicone oil on retinal microcirculation after vitrectomy for rhegmatogenous retinal detachment evaluated by OCT angiography: a literature review.
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        au:
          Christou, Evita Evangelia
          Papaconstantinou, Dimitrios
          Droutsas, Konstantinos
          Stefaniotou, Maria
          Stavrakas, Panagiotis
          Kandarakis, Stylianos
          Petrou, Petros
          Georgalas, Ilias
        affil: Conceptualization, Department of Ophthalmology, Faculty of Medicine, University Hospital of Ioannina, Ioannina, Greece
      sug:
        subj:
          Silicones Therapeutic Use
          Retina Blood Supply
          Eye Surgery Methods
          Microcirculation Drug Effects
          Retinal Detachment Surgery
          Tomography, Optical Coherence
          Angiography
          Recovery
          Retina Anatomy and Histology
          Treatment Outcomes
          Injections
          Silicones Administration and Dosage
          Retina Drug Effects
          Functional Assessment
      ab: Silicone oil (SO) has been widely used as intravitreal tamponade agent for rhegmatogenous retinal detachment (RRD) and has been occasionally associated with incomplete retinal structural and functional recovery. The use of Optical Coherence Tomography Angiography (OCT-A) has recently attracted significant attention for detailed analysis of retinal capillary plexus and blood flow changes as predicting factors for postoperative outcomes. A detailed literature search was performed in PubMed database until October 2022. The following keywords were used: rhegmatogenous retinal detachment, silicone oil, optical coherence tomography angiography, macular microvasculature, peripapillary capillary plexus, vessel density, and foveal avascular zone. We identified and reviewed 19 studies referring to microcirculation alterations of the retinal capillary plexus as seen on OCT-A in eyes treated by vitrectomy with intravitreal SO for RRD. A comprehensive update revealed variability of microcirculation characteristics of the retinal capillary plexus including the macular and the peripapillary capillaries. Further studies are warranted to clarify the OCT-A values in an attempt to identify the potential effect of SO on retinal tissue in clinical practice. A review of the existing literature sheds light on the effect of SO on retinal capillary plexus and the potential impact on functional outcomes after vitrectomy for RRD. This article discusses important aspects of key publications on the topic, highlights the importance to identify distinct alterations of the microvasculature status, and proposes the need for further future research in this field.
      pubtype: Academic Journal
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        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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