MRI-based nomograms and radiomics in presurgical prediction of extraprostatic extension in prostate cancer: a systematic review.

Purpose: Prediction of extraprostatic extension (EPE) is essential for accurate surgical planning in prostate cancer (PCa). Radiomics based on magnetic resonance imaging (MRI) has shown potential to predict EPE. We aimed to evaluate studies proposing MRI-based nomograms and radiomics for EPE predict...

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Publicado en:Abdominal Radiology Vol. 48; no. 7; pp. 2379 - 2401
Autores principales: Calimano-Ramirez, Luis F., Virarkar, Mayur K., Hernandez, Mauricio, Ozdemir, Savas, Kumar, Sindhu, Gopireddy, Dheeraj R., Lall, Chandana, Balaji, K. C., Mete, Mutlu, Gumus, Kazim Z.
Formato: Journal Article
Publicado: Springer Nature Jul2023
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: MRI-based nomograms and radiomics in presurgical prediction of extraprostatic extension in prostate cancer: a systematic review.
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        au:
          Calimano-Ramirez, Luis F.
          Virarkar, Mayur K.
          Hernandez, Mauricio
          Ozdemir, Savas
          Kumar, Sindhu
          Gopireddy, Dheeraj R.
          Lall, Chandana
          Balaji, K. C.
          Mete, Mutlu
          Gumus, Kazim Z.
        affil: Department of Radiology, University of Florida College of Medicine Jacksonville, 32209, Jacksonville, FL, USA
      sug:
      ab: Purpose: Prediction of extraprostatic extension (EPE) is essential for accurate surgical planning in prostate cancer (PCa). Radiomics based on magnetic resonance imaging (MRI) has shown potential to predict EPE. We aimed to evaluate studies proposing MRI-based nomograms and radiomics for EPE prediction and assess the quality of current radiomics literature. Methods: We used PubMed, EMBASE, and SCOPUS databases to find related articles using synonyms for MRI radiomics and nomograms to predict EPE. Two co-authors scored the quality of radiomics literature using the Radiomics Quality Score (RQS). Inter-rater agreement was measured using the intraclass correlation coefficient (ICC) from total RQS scores. We analyzed the characteristic s of the studies and used ANOVAs to associate the area under the curve (AUC) to sample size, clinical and imaging variables, and RQS scores. Results: We identified 33 studies—22 nomograms and 11 radiomics analyses. The mean AUC for nomogram articles was 0.783, and no significant associations were found between AUC and sample size, clinical variables, or number of imaging variables. For radiomics articles, there were significant associations between number of lesions and AUC (p < 0.013). The average RQS total score was 15.91/36 (44%). Through the radiomics operation, segmentation of region-of-interest, selection of features, and model building resulted in a broader range of results. The qualities the studies lacked most were phantom tests for scanner variabilities, temporal variability, external validation datasets, prospective designs, cost-effectiveness analysis, and open science. Conclusion: Utilizing MRI-based radiomics to predict EPE in PCa patients demonstrates promising outcomes. However, quality improvement and standardization of radiomics workflow are needed.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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