Analytical and Non-Analytical Variation May Lead to Inappropriate Antimicrobial Dosing in Neonates: An In Silico Study.

BACKGROUND: Therapeutic drug monitoring (TDM) of aminoglycosides and vancomycin is used to prevent oto- and nephrotoxicity in neonates. Analytical and nonanalytical factors potentially influence dosing recommendations. This study aimed to determine the impact of analytical variation (imprecision and...

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Publicado en:	Clinical Chemistry Vol. 69; no. 6; pp. 637 - 649
Autores principales:	Nguyen, Thi A., Kirubakaran, Ranita, Schultz, Hayley B., Wong, Sherilyn, Reuter, Stephanie E., McMullan, Brendan, Bolisetty, Srinivas, Campbell, Craig, Horvath, Andrea R., Stocker, Sophie L.
Formato:	Journal Article
Publicado:	Oxford University Press / USA Jun2023
Acceso en línea:	Ver este registro en EBSCOhost