Dynamics of annatto pigment synthesis and accumulation in seeds of Bixa orellana L. revealed by integrated chemical, anatomical, and RNA-Seq analyses.

Bixin is a commercially valuable apocarotenoid pigment found in the seed aril of Bixa orellana. The dynamics and regulation of its biosynthesis and accumulation during seed development remain largely unknown. Here, we combined chemical, anatomical, and transcriptomic data to provide stage-specific r...

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Publicado en:Protoplasma Vol. 260; no. 4; pp. 1207 - 1220
Autores principales: Moreira, Viviane Santos, de Souza, Vinicius Carius, Soares, Virgínia Lúcia Fontes, Sousa, Aurizangela Oliveira, de Nascimento, Katiucia Ticila de Souza, de Santana, Monique Reis, Rebouças, Tiyoko Nair Hojo, Leitão, Carlos André Espolador, Goliatt, Priscila Vanessa Zabala Capriles, Faria, Daniele Vidal, Otoni, Wagner Campos, Costa, Marcio Gilberto Cardoso
Formato: Journal Article
Publicado: Springer Nature Jul2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2023
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00709-023-01842-w
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        atl: Dynamics of annatto pigment synthesis and accumulation in seeds of Bixa orellana L. revealed by integrated chemical, anatomical, and RNA-Seq analyses.
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          Moreira, Viviane Santos
          de Souza, Vinicius Carius
          Soares, Virgínia Lúcia Fontes
          Sousa, Aurizangela Oliveira
          de Nascimento, Katiucia Ticila de Souza
          de Santana, Monique Reis
          Rebouças, Tiyoko Nair Hojo
          Leitão, Carlos André Espolador
          Goliatt, Priscila Vanessa Zabala Capriles
          Faria, Daniele Vidal
          Otoni, Wagner Campos
          Costa, Marcio Gilberto Cardoso
        affil: Instituto Federal de Educação Ciência E Tecnologia da Bahia, 48500-000, Euclides da Cunha, Bahia, Brazil
      sug:
      ab: Bixin is a commercially valuable apocarotenoid pigment found in the seed aril of Bixa orellana. The dynamics and regulation of its biosynthesis and accumulation during seed development remain largely unknown. Here, we combined chemical, anatomical, and transcriptomic data to provide stage-specific resolution of the cellular and molecular events occurring during B. orellana seed development. Seeds at five developmental stages (S1–S5) were used for analysis of bixin content and seed anatomy, and three of them (S1, S3, and S4) were selected for Illumina HiSeq sequencing. Bixin accumulated in large quantities in seeds compared with other tissues analyzed, particularly during the S2 stage, peaking at the S4 stage, and then decreasing slightly in the S5 stage. Anatomical analysis revealed that bixin accumulated in the large central vacuole of specialized cells, which were scattered throughout the developing mesotesta at the S2 stage, but enlarged progressively at later stages, until they occupied most of the parenchyma in the aril. A total of 13 million reads were generated and assembled into 73,381 protein-encoding contigs, from which 312 were identified as containing 1-deoxy-D-xylulose-5-phosphate/2-C-methyl-D-erythritol-4-phosphate (DOXP/MEP), carotenoid, and bixin pathways genes. Differential transcriptome expression analysis of these genes revealed that 50 of them were sequentially and differentially expressed through the seed developmental stages analyzed, including seven carotenoid cleavage dioxygenases, eight aldehyde dehydrogenases, and 22 methyltransferases. Taken together, these results show that bixin synthesis and accumulation in seeds of B. orellana are a developmentally regulated process involving the coordinated expression of DOXP/MEP, carotenoid, and bixin biosynthesis genes.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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