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Acné y vitamina D.

Acne is a very common inflammatory skin disease, especially in adolescents and young adults, it has a chronic evolution that can lead to the formation of scars and hyperpigmentation. The pathogenesis of acne covers four aspects: hyper seborrhea, altered keratinization of the pilosebaceous duct, prol...

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Published in:Dermatología Revista Mexicana Vol. 67; no. 3; pp. 372 - 380
Main Authors: Arteaga-Rodríguez, Daniela, Ramón Magaña-García, Mario
Format: Article
Published: Edicion y Farmacia S.A. de C.V. may/jun2023
Online Access:View this record in EBSCOhost
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      dt: may/jun2023
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        atl: Acné y vitamina D.
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          Arteaga-Rodríguez, Daniela
          Ramón Magaña-García, Mario
        affil:
          Servicio de Dermatologi'a
          Jefe del Servicio de Dermatologi'a. Hospital General de Me'xico Dr. Eduardo Liceaga, Ciudad de Me'xico
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        Acne
        Keratinocyte
        Seborrhea
        Vitamin D
        Acné
        queratinocito
        seborrea
        vitamina D
      ab:
        Acne is a very common inflammatory skin disease, especially in adolescents and young adults, it has a chronic evolution that can lead to the formation of scars and hyperpigmentation. The pathogenesis of acne covers four aspects: hyper seborrhea, altered keratinization of the pilosebaceous duct, proliferation of Cutibacterium acnes, and inflammation. Recent studies highlight that inflammation is critical in the formation, development, and resolution of acne. Vitamin D is a fat-soluble vitamin mainly metabolized in the epidermis, with regulatory effects on the immune system, actions on the proliferation and differentiation of keratinocytes and sebocytes, and anti-comedogenic and antioxidant properties; therefore, vitamin D deficiency may be involved in the development of acne and possibly provide a new option for the treatment of this disease.
        El acné es una enfermedad inflamatoria de la piel muy común especialmente en adolescentes y adultos jóvenes, tiene una evolución crónica que puede conducir a la formación de cicatrices e hiperpigmentación. La patogénesis del acné cubre cuatro aspectos: hiperseborrea, queratinización alterada del conducto pilosebáceo, proliferación de Cutibacterium acnes e inflamación. Los estudios recientes destacan que la inflamación es crítica en la formación, desarrollo y alivio del acné. La vitamina D es una vitamina liposoluble principalmente metabolizada en la epidermis, con efectos reguladores del sistema inmunitario, acciones en la proliferación y diferenciación de queratinocitos y sebocitos, y propiedades anticomedogénicas y antioxidantes; por lo que la deficiencia de vitamina D puede estar implicada en la aparición del acné y posiblemente proporcione una nueva opción para el tratamiento de esta enfermedad.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: Spanish
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      custom: Copyright of Dermatología Revista Mexicana is the property of Edicion y Farmacia S.A. de C.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use.
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