The efficacy of an internet‐based cognitive behavioral program added to treatment‐as‐usual for alcohol‐dependent patients in primary care: a randomized controlled trial.

Background and Aims: Most alcohol‐dependent people have a moderate level of dependence. General practitioners (GPs) hesitate to engage in this area, and need to have access to treatment they find applicable and feasible to use. The aim of this present study was to test if an open‐ended internet‐base...

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Publicado en:Addiction Vol. 118; no. 7; pp. 1232 - 1244
Autores principales: Hyland, Karin, Hammarberg, Anders, Hedman‐Lagerlöf, Erik, Johansson, Magnus, Lindner, Philip, Andreasson, Sven
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Wiley-Blackwell Jul2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2023
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: The efficacy of an internet‐based cognitive behavioral program added to treatment‐as‐usual for alcohol‐dependent patients in primary care: a randomized controlled trial.
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          Hyland, Karin
          Hammarberg, Anders
          Hedman‐Lagerlöf, Erik
          Johansson, Magnus
          Lindner, Philip
          Andreasson, Sven
        affil: Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
      sug:
        subj:
          Internet-Based Intervention
          Cognitive Therapy
          Alcoholism Therapy
          Primary Health Care
          Treatment Outcomes
          Human
          Randomized Controlled Trials
          After Care
          Sweden
          Descriptive Statistics
          Middle Age
          Male
          Female
          Random Assignment
          Feedback
          Physicians, Family
          Biological Markers
          Confidence Intervals
          Funding Source
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background and Aims: Most alcohol‐dependent people have a moderate level of dependence. General practitioners (GPs) hesitate to engage in this area, and need to have access to treatment they find applicable and feasible to use. The aim of this present study was to test if an open‐ended internet‐based cognitive–behavioral therapy (iCBT) program added to treatment‐as‐usual (TAU) is more effective than TAU‐only for alcohol‐dependent patients in primary care. Design, Setting and Participants: The present study was a two‐group, parallel, randomized controlled superiority trial comparing iCBT+TAU versus TAU‐only at 3‐ and 12‐month follow‐ups. TAU was delivered at 14 primary care centers in Stockholm, Sweden. A total of 264 patients (mean age 51 years, of whom 148 were female and 116 were male) with alcohol dependence and hazardous alcohol consumption were enrolled between September 2017 and November 2019. Measurements: Participants were randomized at a ratio of 1:1 to iCBT, as a self‐help intervention added to TAU (n = 132) or to TAU‐only (n = 132). The GPs gave participants in both treatment arms feedback on the assessments and biomarkers and offered TAU at the primary care center. Primary outcome was weekly alcohol consumption in g/week at 12‐month follow‐up, analyzed according to intention‐to‐treat (n = 132 + 132). The per‐protocol analysis included participants who completed at least one module of iCBT (n = 102 + 132). Findings There was no significant difference in weekly alcohol consumption between iCBT+TAU and TAU in the intention‐to‐treat (ITT) analysis at 12‐month follow‐up [iCBT+TAU = 133.56 (95% confidence interval, CI = 100.94–166.19) and TAU = 176.20 (95% CI = 144.04–208.35), P = 0.068, d = 0.23]. In the per‐protocol analysis, including only those who initiated iCBT, the iCBT+TAU group showed lower mean weekly alcohol consumption compared with TAU [iCBT+TAU = 107.46 (95% CI = 71.17–143.74), TAU = 176.00 (95% CI = 144.21–207.80), P = 0.010, d = 0.42]. Conclusions: In Sweden, an internet‐based cognitive–behavioral program added to treatment‐as‐usual to reduce alcohol consumption showed weak evidence of a benefit at 12 months in the intention‐to‐treat analysis and good evidence of a benefit in the per‐protocol analysis.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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