Administration of immune checkpoint inhibitors at rural towns using the Teleoncology model of care—A North Queensland perspective.
Objective: This study aimed at evaluating the safety of administering immune checkpoint inhibitors (ICIs) and monitoring for immune‐related adverse events (irAEs) using the Teleoncology model of care. Design: A retrospective cohort study comparing two patient groups. Setting: The North Queensland Te...
| Publicado en: | Australian Journal of Rural Health Vol. 31; no. 3; pp. 540 - 546 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jun2023
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164352720&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164352720 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10385282 FQO jtl: Australian Journal of Rural Health issn: 10385282 maglogo: Y pubinfo: dt: Jun2023 vid: 31 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 164352720 162966003 164352720 164352720 10.1111/ajr.12984 164352720 ppf: 540 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Administration of immune checkpoint inhibitors at rural towns using the Teleoncology model of care—A North Queensland perspective. aug: au: Kang, Sebastian Fletcher, James Htut, Saw Brown, Amy Lyle, Megan Sabesan, Sabe Joshi, Abhishek affil: Townsville Cancer Centre, Townsville Hospital Health Service, Townsville Queensland,, Australia sug: subj: Immune Checkpoint Inhibitors Administration and Dosage Patient Safety Telemedicine Oncologic Care Rural Areas Immune Checkpoint Inhibitors Adverse Effects Immunity Human Retrospective Design Prospective Studies Descriptive Statistics Data Analysis Software Immunotherapy Mann-Whitney U Test Fisher's Exact Test Wilcoxon Rank Sum Test Male Female Adult Middle Age Aged Aged, 80 and Over Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Objective: This study aimed at evaluating the safety of administering immune checkpoint inhibitors (ICIs) and monitoring for immune‐related adverse events (irAEs) using the Teleoncology model of care. Design: A retrospective cohort study comparing two patient groups. Setting: The North Queensland Teleoncology Network (NQTN) operated by the Townsville (THHS) and Cairns Hospital Health Services (CHHS) with the Townsville Cancer Centre (TCC) acting as the control group setting. Participants: Patients who received ICI treatment via the NQTN between January 2015 and April 2019. Patients who received ICI at the TCC over the same time period were used for comparison. Main Outcome Measures: Rates of high‐grade irAEs and irAE‐related deaths. Results: Fifty‐two patients received a total of 822 cycles of ICIs via the Teleoncology model through NQTN. Over the same time period, 142 patients received a total of 1521 cycles at the TCC. There were no significant differences in all demographic characteristics between either group, including tumour profile and Indigenous status. There were no statistically significant differences between the rates of high‐grade irAE across multiple body organ systems (p = 0.151) and rate of hospital admissions (13.5% (NQTN) vs 5.6% (TCC), p = 0.702). There were no irAE‐related deaths in either group. Conclusions: The results suggest that with adequate governance and clinical resources, ICIs can be administered safely using Teleoncology models to rural and remote towns. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|