Gait performance and prefrontal cortex activation during single and dual task walking in older adults with different cognitive levels.
Background: Growing evidence shows the cognitive function influences the motor performance. The prefrontal cortex (PFC) as a part of the executive locomotor pathway is also important for cognitive function. This study investigated the differences in motor function and brain activity among older adul...
| Publicado en: | Frontiers in Aging Neuroscience pp. 1 - 13 |
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| Autores principales: | , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Frontiers Media S.A.
2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164380398&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164380398 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16634365 BG2U jtl: Frontiers in Aging Neuroscience issn: 16634365 maglogo: N pubinfo: dt: 2023 pid: 40038 pub: Frontiers Media S.A. artinfo: ui: 164380398 164380398 164380398 10.3389/fnagi.2023.1177082 164380398 ppf: 1 ppct: 12 formats: tig: atl: Gait performance and prefrontal cortex activation during single and dual task walking in older adults with different cognitive levels. aug: au: Wei-Han Weng Yea-Ru Yang Nai-Chen Yeh Pei-Hsin Ku Po-Shan Wang Ying-Yi Liao Ray-Yau Wang affil: Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University, Taipei, Taiwan. sug: subj: Gait Prefrontal Cortex Physiology Walking Physiology Cognition Task Performance and Analysis Human Male Female Aged Aged, 80 and Over Data Analysis Software One-Way Analysis of Variance Chi Square Test Kruskal-Wallis Test Post Hoc Analysis Spearman's Rank Correlation Coefficient Multiple Regression Linear Regression Sample Size Descriptive Statistics Funding Source Mild Cognitive Impairment Dementia Comparative Studies Cross Sectional Studies Attention Memory Aged: 65+ years Aged, 80 & over Male Female ab: Background: Growing evidence shows the cognitive function influences the motor performance. The prefrontal cortex (PFC) as a part of the executive locomotor pathway is also important for cognitive function. This study investigated the differences in motor function and brain activity among older adults with different cognitive levels, and examined the significance of cognition on motor functions. Methods: Normal control (NC), individuals with mild cognitive impairment (MCI) or mild dementia (MD) were enrolled in this study. All participants received a comprehensive assessment including cognitive function, motor function, PFC activity during walking, and fear of fall. The assessment of cognitive function included general cognition, attention, executive function, memory, and visuospatial. The assessment of motor function included timed up and go (TUG) test, single walking (SW), and cognitive dual task walking (CDW). Results: Individuals with MD had worse SW, CDW and TUG performance as compared to individuals with MCI and NC. These gait and balance performance did not differ significantly between MCI and NC. Motor functions all correlated with general cognition, attention, executive function, memory, and visuo-spatial ability. Attention ability measured by trail making test A (TMT-A) was the best predictor for TUG and gait velocity. There were no significant differences in PFC activity among three groups. Nevertheless, the PFC activated more during CDW as compared with SW in individuals with MCI (p = 0.000), which was not demonstrated in the other two groups. Conclusion: MD demonstrated worse motor function as compared to NC and MCI. The greater PFC activity during CDW in MCI may be considered as a compensatory strategy for maintaining the gait performance. Motor function was related to the cognitive function, and the TMT A was the best predictor for the gait related performance in present study among older adults. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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