A meta-analysis of the association between Helicobacter pylori infection and risk of hepatic encephalopathy.
Background Although the association between Helicobacter pylori (H. pylori) infection and hepatic encephalopathy (HE) has been confirmed through some research, the results of these relevant studies still remain controversial. We conducted an updated meta-analysis based on published studies to addres...
| Publicado en: | Journal of Public Health Vol. 45; no. 2; pp. 321 - 330 |
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| Autores principales: | , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Oxford University Press / USA
Jun2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164395652&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164395652 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17413842 1CA0 jtl: Journal of Public Health issn: 17413842 maglogo: N pubinfo: dt: Jun2023 vid: 45 iid: 2 pid: 622 pub: Oxford University Press / USA artinfo: ui: 164395652 164395652 164395652 10.1093/pubmed/fdac078 164395652 ppf: 321 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A meta-analysis of the association between Helicobacter pylori infection and risk of hepatic encephalopathy. aug: au: Li, Junwei Yu, Hongwei Wang, Yuexia Wang, Bin Zhang, Rongguang Chen, Shuaiyin Duan, Guangcai affil: Department of Epidemiology , College of Public Health, Zhengzhou University , Zhengzhou , China sug: subj: Helicobacter Infections Complications Hepatic Encephalopathy Risk Factors Risk Assessment Human Systematic Review Meta Analysis Funding Source Odds Ratio Confidence Intervals PubMed Embase Medline Descriptive Statistics Scales Chi Square Test ab: Background Although the association between Helicobacter pylori (H. pylori) infection and hepatic encephalopathy (HE) has been confirmed through some research, the results of these relevant studies still remain controversial. We conducted an updated meta-analysis based on published studies to address this issue. Methods A systematic search was conducted, reviewing all studies about the association between H. pylori infection and HE, through November 2021. The outcome measures were presented as odds ratios (ORs) with 95% confidence intervals (CIs). Results In total, 13 studies provided data from 2784 subjects. H. pylori infection increased the risk of HE by 32% (OR = 2.32, 95% CI: 1.78–3.04). The effect became greater after hepatic encephalopathy was divided into overt HE and minimal hepatic encephalopathy (MHE) (HE OR = 2.66, 95% CI: 2.01–3.51, MHE OR = 1.74, 95% CI: 1.10–2.76). After H. pylori eradication, the risk of HE was reduced by 64%. Conclusions H. pylori infection is significantly associated with HE, and the infection rate of H. pylori also increases with the severity of HE. Eradication of H. pylori has a protective effect on HE. Therefore, it is necessary to eradicate H. pylori in HE treatments. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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