Spatial distribution and computational modeling for mapping of tuberculosis in Pakistan.

Background Tuberculosis (TB) like many other infectious diseases has a strong relationship with climatic parameters. Methods The present study has been carried out on the newly diagnosed sputum smear-positive pulmonary TB cases reported to National TB Control Program across Pakistan from 2007 to 202...

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Published in:Journal of Public Health Vol. 45; no. 2; pp. 338 - 347
Main Authors: Khaliq, Aasia, Ashraf, Uzma, Chaudhry, Muhammad N, Shahid, Saher, Sajid, Muhammad A, Javed, Maryam
Format: pictorial research tables/charts Journal Article
Published: Oxford University Press / USA Jun2023
Online Access:View this record in EBSCOhost
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      dt: Jun2023
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      pub: Oxford University Press / USA
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        10.1093/pubmed/fdac125
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        atl: Spatial distribution and computational modeling for mapping of tuberculosis in Pakistan.
      aug:
        au:
          Khaliq, Aasia
          Ashraf, Uzma
          Chaudhry, Muhammad N
          Shahid, Saher
          Sajid, Muhammad A
          Javed, Maryam
        affil: Department of Life Sciences, Lahore University of Management Sciences (LUMS) , Lahore , Pakistan
      sug:
        subj:
          Tuberculosis Epidemiology
          Disease Hotspot
          Computer Simulation
          Concept Mapping
          Human
          Pakistan
          Tuberculosis Risk Factors
          Incidence
          Descriptive Statistics
          Comparative Studies
          Machine Learning
          Algorithms
          Support Vector Machine
          Risk Assessment
      ab: Background Tuberculosis (TB) like many other infectious diseases has a strong relationship with climatic parameters. Methods The present study has been carried out on the newly diagnosed sputum smear-positive pulmonary TB cases reported to National TB Control Program across Pakistan from 2007 to 2020. In this study, spatial and temporal distribution of the disease was observed through detailed district wise mapping and clustered regions were also identified. Potential risk factors associated with this disease depending upon population and climatic variables, i.e. temperature and precipitation were also identified. Results Nationwide, the incidence rate of TB was observed to be rising from 7.03% to 11.91% in the years 2007–2018, which then started to decline. However, a declining trend was observed after 2018–2020. The most populous provinces, Punjab and Sindh, have reported maximum number of cases and showed a temporal association as the climatic temperature of these two provinces is higher with comparison to other provinces. Machine learning algorithms Maxent, Support Vector Machine (SVM), Environmental Distance (ED) and Climate Space Model (CSM) predict high risk of the disease with14.02%, 24.75%, 34.81% and 43.89% area, respectively. Conclusion SVM has a higher significant probability of prediction in the diseased area with a 1.86 partial receiver-operating characteristics (ROC) value as compared with other models.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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