ORIENTATE: automated machine learning classifiers for oral health prediction and research.

Background: The application of data-driven methods is expected to play an increasingly important role in healthcare. However, a lack of personnel with the necessary skills to develop these models and interpret its output is preventing a wider adoption of these methods. To address this gap, we introd...

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Publicado en:BMC Oral Health Vol. 23; no. 1; pp. 1 - 20
Autores principales: Gomez-Rios, Inmaculada, Egea-Lopez, Esteban, Ortiz Ruiz, Antonio José
Formato: pictorial research tables/charts Journal Article
Publicado: BioMed Central 6/20/2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 6/20/2023
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      pub: BioMed Central
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        10.1186/s12903-023-03112-w
        164419034
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        atl: ORIENTATE: automated machine learning classifiers for oral health prediction and research.
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        au:
          Gomez-Rios, Inmaculada
          Egea-Lopez, Esteban
          Ortiz Ruiz, Antonio José
        affil: Department of Dermatology, Stomatology, Radiology and Physical Medicine, Universidad de Murcia, Murcia, Spain
      sug:
        subj:
          Automation
          Machine Learning
          Algorithms
          Oral Health
          Prediction Models
          Human
          Descriptive Statistics
          T-Tests
          Mann-Whitney U Test
          Pearson's Correlation Coefficient
          Chi Square Test
          Fisher's Exact Test
          ROC Curve
          Inferential Statistics
          Sedation
          Funding Source
      ab: Background: The application of data-driven methods is expected to play an increasingly important role in healthcare. However, a lack of personnel with the necessary skills to develop these models and interpret its output is preventing a wider adoption of these methods. To address this gap, we introduce and describe ORIENTATE, a software for automated application of machine learning classification algorithms by clinical practitioners lacking specific technical skills. ORIENTATE allows the selection of features and the target variable, then automatically generates a number of classification models and cross-validates them, finding the best model and evaluating it. It also implements a custom feature selection algorithm for systematic searches of the best combination of predictors for a given target variable. Finally, it outputs a comprehensive report with graphs that facilitates the explanation of the classification model results, using global interpretation methods, and an interface for the prediction of new input samples. Feature relevance and interaction plots provided by ORIENTATE allow to use it for statistical inference, which can replace and/or complement classical statistical studies. Results: Its application to a dataset with healthy and special health care needs (SHCN) children, treated under deep sedation, was discussed as case study. On the example dataset, despite its small size, the feature selection algorithm found a set of features able to predict the need for a second sedation with a f1 score of 0.83 and a ROC (AUC) of 0.92. Eight predictive factors for both populations were found and ordered by the relevance assigned to them by the model. A discussion of how to derive inferences from the relevance and interaction plots and a comparison with a classical study is also provided. Conclusions: ORIENTATE automatically finds suitable features and generates accurate classifiers which can be used in preventive tasks. In addition, researchers without specific skills on data methods can use it for the application of machine learning classification and as a complement to classical studies for inferential analysis of features. In the case study, a high prediction accuracy for a second sedation in SHCN children was achieved. The analysis of the relevance of the features showed that the number of teeth with pulpar treatments at the first sedation is a predictive factor for a second sedation.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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