The relationship between life satisfaction, personal health, quality of life, and medication adherence among adolescents living with HIV in southwestern Uganda.

Purpose: Adolescents living with HIV (ALHIV) are at high risk for adherence to antiretroviral (ART) treatment and poor health-seeking behaviors, both of which potentially compromise their quality of and satisfaction with life. This study, therefore, seeks to examine the relationship between physical...

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Publicado en:Journal of Public Health: From Theory to Practice (2198-1833) Vol. 31; no. 7; pp. 1177 - 1185
Autores principales: Byansi, William, Nabunya, Proscovia, Muwanga, Joelynn, Mwebembezi, Abel, Damulira, Christopher, Mukasa, Barbara, Zmachinski, Lily, Nattabi, Jennifer, Brathwaite, Rachel, Namuwonge, Flavia, Bahar, Ozge Sensoy, Neilands, Torsten B., Mellins, Claude A., Ssewamala, Fred M.
Formato: Artículo
Publicado: Springer Nature Jul2023
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2023
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      pub: Springer Nature
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        10.1007/s10389-021-01632-9
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        atl: The relationship between life satisfaction, personal health, quality of life, and medication adherence among adolescents living with HIV in southwestern Uganda.
      aug:
        au:
          Byansi, William
          Nabunya, Proscovia
          Muwanga, Joelynn
          Mwebembezi, Abel
          Damulira, Christopher
          Mukasa, Barbara
          Zmachinski, Lily
          Nattabi, Jennifer
          Brathwaite, Rachel
          Namuwonge, Flavia
          Bahar, Ozge Sensoy
          Neilands, Torsten B.
          Mellins, Claude A.
          Ssewamala, Fred M.
        affil:
          Brown School, Washington University in St. Louis, One Brookings Drive, 63130, St. Louis, MO, USA
          International Center for Child Health and Development Field Office, Plot 23 Circular Rd, Masaka, Uganda
          Reach the Youth Uganda, Kampala, Uganda
          MildMay Uganda, Kampala, Uganda
          School of Medicine, University of California San Francisco, 550 16th Street, 94158, San Francisco, CA, USA
          Columbia University Medical Center, 630 West 168th Street, 10032, New York, NY, USA
      su:
        Uganda
        Satisfaction
        Health status indicators
        Quality of life
        Drugs
        Patient compliance
        Sociodemographic factors
        Adolescence
        HIV infections
        Antiretroviral agents
        Regression analysis
        Research funding
        Psychology of HIV-positive persons
      sug:
        subj:
          Satisfaction
          Health status indicators
          Quality of life
          Drugs
          Patient compliance
          Sociodemographic factors
          Adolescence
          Uganda
          Drugs and Druggists' Sundries Merchant Wholesalers
          Pharmaceuticals and pharmacy supplies merchant wholesalers
          Pharmaceutical and medicine manufacturing
          HIV infections
          Antiretroviral agents
          Regression analysis
          Research funding
          Psychology of HIV-positive persons
      keyword:
        Adolescents living with HIV
        ART adherence
        Life satisfaction
        Sub-Saharan Africa
        Adolescents living with HIV
        ART adherence
        Life satisfaction
        Sub-Saharan Africa
      ab: Purpose: Adolescents living with HIV (ALHIV) are at high risk for adherence to antiretroviral (ART) treatment and poor health-seeking behaviors, both of which potentially compromise their quality of and satisfaction with life. This study, therefore, seeks to examine the relationship between physical health, pediatric quality of life, life satisfaction, and medication adherence among ALHIV in southwestern Uganda. Methods: Baseline data from the Suubi+Adherence study, 2012–2018, that recruited 702 adolescents, aged 10–16 years, living with HIV in Uganda were analyzed. To account for overdispersion, negative binomial regression analyses were used to examine the impact of physical health, pediatric quality of life, and life satisfaction on self-reported medication adherence. We controlled for participants' socio-demographic factors. Results: Results indicated that after adjusting for socio-demographic characteristics, adolescents' reported satisfaction with life was associated with a decrease in the reported number of days missed taking medication by 41.2% (IRR (incidence risk ratio) = 0.588; p (p value) = 0.014). On the other hand, the low level of pediatric quality of life was associated with a 5% increase in the reported number of days missed taking medication (IRR = 1.055, p = 0.044). Personal health was not statistically significant in the model. Conclusion: Our study findings indicated that quality of life and life satisfaction are significantly associated with antiretroviral (ART) medication among ALHIV. Hence, strengthening existing support systems and creating additional support for optimal ART adherence and treatment outcomes for ALHIV in low-resource communities might be beneficial. Moreover, with the increasing HIV prevalence rates among adolescents, effective and comprehensive efforts that are responsive to the special needs of ALHIV must be developed to ensure optimal adherence to ART medication as it leads to low vertical infection and superinfection rates.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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