Extended Multimodal Flat Detector CT Imaging in Acute Ischemic Stroke: A Pilot Study.

By using Flat detector computed tomography (FD-CT), a one-stop-shop approach in the diagnostic workup of acute ischemic stroke (AIS) might be achieved. Although information on upstream vessels is warranted, dedicated FD-CT protocols which include the imaging of the cervical vasculature are still lac...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 3; pp. 1198 - 1208
Autores principales: Hoelter, Philip, Lang, Stefan, Beuscher, Vanessa, Kallmuenzer, Bernd, Manhart, Michael, Schwab, Stefan, Doerfler, Arnd
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Jun2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2023
      vid: 36
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-022-00699-4
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        atl: Extended Multimodal Flat Detector CT Imaging in Acute Ischemic Stroke: A Pilot Study.
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          Hoelter, Philip
          Lang, Stefan
          Beuscher, Vanessa
          Kallmuenzer, Bernd
          Manhart, Michael
          Schwab, Stefan
          Doerfler, Arnd
        affil: Department of Neuroradiology, University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen- Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany
      sug:
        subj:
          Ischemic Stroke Radiography
          Acute Disease
          Diagnostic Imaging Methods
          Tomography, X-Ray Computed Methods
          Cerebral Ischemia Radiography
          Stroke Patients
          Human
          Male
          Female
          Pilot Studies
          Retrospective Design
          Prospective Studies
          Workflow
          Groin
          Angiography
          Cerebral Hemorrhage
          Perfusion
          Time Factors
          Descriptive Statistics
          Comparative Studies
          Funding Source
          Male
          Female
      ab: By using Flat detector computed tomography (FD-CT), a one-stop-shop approach in the diagnostic workup of acute ischemic stroke (AIS) might be achieved. Although information on upstream vessels is warranted, dedicated FD-CT protocols which include the imaging of the cervical vasculature are still lacking. We aimed to prospectively evaluate the implementation of a new multimodal FD-CT protocol including cervical vessel imaging in AIS patients. In total, 16 patients were included in this study. Eight patients with AIS due to large vessel occlusion (LVO) prospectively received a fully multimodal FD-CT imaging, including non-enhanced flat detector computed tomography (NE-FDCT), dynamic perfusion flat detector computed tomography (FD-CTP) and flat detector computed tomography angiography (FD-CTA) including cervical imaging. For comparison of time metrics and image quality, eight AIS patients, which received multimodal CT imaging, were included retrospectively. Although image quality of NE-FDCT and FD-CTA was rated slightly lower than NE-CT and CTA, all FD-CT datasets were of diagnostic quality. Intracerebral hemorrhage exclusion and LVO detection was reliably possible. Median door-to-image time was comparable for the FD-CT group and the control group (CT:30 min, IQR27-58; FD-CT:44.5 min, IQR31-55, p = 0.491). Door-to-groin-puncture time (CT:79.5 min, IQR65-90; FD-CT:59.5 min, IQR51-67; p = 0.016) and image-to-groin-puncture time (CT:44 min, IQR30-50; FD-CT:14 min, IQR12-18; p < 0.001) were significantly shorter, when patients were directly transferred to the angiosuite, where FD-CT took place. Our study indicates that using a new fully multimodal FD-CT approach including imaging of cervical vessels for first-line imaging in AIS patients is feasible and comparable to multimodal CT imaging with substantial potential to streamline the stroke workflow.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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