An Unsupervised Learning-Based Regional Deformable Model for Automated Multi-Organ Contour Propagation.

The aim of this study is to evaluate a regional deformable model based on a deep unsupervised learning model for automatic contour propagation in breast cone-beam computed tomography–guided adaptive radiation therapy. A deep unsupervised learning model was introduced to map breast's tumor bed, clini...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 3; pp. 923 - 932
Autores principales: Liang, Xiaokun, Dai, Jingjing, Zhou, Xuanru, Liu, Lin, Zhang, Chulong, Jiang, Yuming, Li, Na, Niu, Tianye, Xie, Yaoqin, Dai, Zhenhui, Wang, Xuetao
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Jun2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2023
      vid: 36
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-023-00779-z
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        atl: An Unsupervised Learning-Based Regional Deformable Model for Automated Multi-Organ Contour Propagation.
      aug:
        au:
          Liang, Xiaokun
          Dai, Jingjing
          Zhou, Xuanru
          Liu, Lin
          Zhang, Chulong
          Jiang, Yuming
          Li, Na
          Niu, Tianye
          Xie, Yaoqin
          Dai, Zhenhui
          Wang, Xuetao
        affil: Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, 518055, Shenzhen, Guangdong, China
      sug:
        subj:
          Image Processing, Computer Assisted Education
          Tomography, X-Ray Computed Education
          Learning Methods
          Models, Educational
          Breast Neoplasms Radiotherapy
          Human
          Deep Learning
          Retrospective Design
          Record Review
          Algorithms
          Funding Source
      ab: The aim of this study is to evaluate a regional deformable model based on a deep unsupervised learning model for automatic contour propagation in breast cone-beam computed tomography–guided adaptive radiation therapy. A deep unsupervised learning model was introduced to map breast's tumor bed, clinical target volume, heart, left lung, right lung, and spinal cord from planning computed tomography to cone-beam CT. To improve the traditional image registration method's performance, we used a regional deformable framework based on the narrow-band mapping, which can mitigate the effect of the image artifacts on the cone-beam CT. We retrospectively selected 373 anonymized cone-beam CT volumes from 111 patients with breast cancer. The cone-beam CTs are divided into three sets. 311 / 20 / 42 cone-beam CT images were used for training, validating, and testing. The manual contour was used as reference for the testing set. We compared the results between the reference and the model prediction for evaluating the performance. The mean Dice between manual reference segmentations and the model predicted segmentations for breast tumor bed, clinical target volume, heart, left lung, right lung, and spinal cord were 0.78 ± 0.09, 0.90 ± 0.03, 0.88 ± 0.04, 0.94 ± 0.03, 0.95 ± 0.02, and 0.77 ± 0.07, respectively. The results demonstrated a good agreement between the reference and the proposed contours. The proposed deep learning–based regional deformable model technique can automatically propagate contours for breast cancer adaptive radiotherapy. Deep learning in contour propagation was promising, but further investigation was warranted.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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