Higher Levels of Stress and Neuropsychological Symptoms Are Associated With a High Nausea Profile in Patients With Cancer Receiving Chemotherapy.

OBJECTIVES: To evaluate differences in the severity of global, cancer-specific, and cumulative life stress, resilience, and common neuropsychological symptoms among four subgroups of patients with distinct chemotherapy-induced nausea (CIN) profiles. SAMPLE & SETTING: Adult patients with cancer (N =...

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Published in:Oncology Nursing Forum Vol. 50; no. 4; pp. 461 - 478
Main Authors: Singh, Komal P., Cooper, Bruce A., Tofthagen, Cindy S., Fryer, John D., Singh, Parminder, Pituch, Keenan, Qiyun Zhu, Haiwei Gu, Hammer, Marilyn J., Conley, Yvette P., Levine, Jon D., Miaskowski, Christine
Format: research tables/charts Journal Article
Published: Oncology Nursing Society Jul2023
Online Access:View this record in EBSCOhost
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      dt: Jul2023
      vid: 50
      iid: 4
      pid: 12496
      pub: Oncology Nursing Society
      place: Pittsburgh, Pennsylvania
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        10.1188/23.ONF.461-473
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        atl: Higher Levels of Stress and Neuropsychological Symptoms Are Associated With a High Nausea Profile in Patients With Cancer Receiving Chemotherapy.
      aug:
        au:
          Singh, Komal P.
          Cooper, Bruce A.
          Tofthagen, Cindy S.
          Fryer, John D.
          Singh, Parminder
          Pituch, Keenan
          Qiyun Zhu
          Haiwei Gu
          Hammer, Marilyn J.
          Conley, Yvette P.
          Levine, Jon D.
          Miaskowski, Christine
        affil: Nurse scientist at the Mayo Clinic Cancer Center and an assistant professor in the Edson College of Nursing and Health Innovation at Arizona State University
      sug:
        subj:
          Severity of Illness Indices
          Neoplasms Psychosocial Factors
          Stress, Psychological Complications
          Hardiness
          Neuropsychology
          Neurologic Manifestations Complications
          Chemotherapy, Cancer Adverse Effects
          Nausea Chemically Induced
          Cancer Survivors
          Nausea Risk Factors
          Risk Assessment
          Human
          Scales
          Nonparametric Statistics
          Parametric Statistics
          Depression
          Anxiety
          Sleep Disorders
          Cancer Fatigue
          Cancer Pain
          Cognition Disorders
          Conceptual Framework
          Karnofsky Performance Status
          Questionnaires
          State-Trait Anxiety Inventory
          Brief Pain Inventory
          Psychological Tests
          Descriptive Statistics
          Data Analysis Software
          Chi Square Test
          Post Hoc Analysis
          Mental Disorders
      ab: OBJECTIVES: To evaluate differences in the severity of global, cancer-specific, and cumulative life stress, resilience, and common neuropsychological symptoms among four subgroups of patients with distinct chemotherapy-induced nausea (CIN) profiles. SAMPLE & SETTING: Adult patients with cancer (N = 1,343) receiving chemotherapy. METHODS & VARIABLES: Patients completed stress, resilience, and neuropsychological symptom severity measures. The Memorial Symptom Assessment Scale was used to assess CIN occurrence six times over two cycles of chemotherapy. Parametric and nonparametric statistics were used to evaluate differences among subgroups of patients with distinct CIN profiles. RESULTS: The high class had significantly higher levels of global, cancer-specific, and cumulative life stress; significantly higher levels of depression, anxiety, sleep disturbance, morning and evening fatigue, and pain; and lower levels of morning and evening energy and cognitive dysfunction. IMPLICATIONS FOR NURSING: Clinicians need to evaluate CIN occurrence across each cycle of chemotherapy and assess patients for various types of stress and common neuropsychological symptoms.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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