Wireless Optoelectronic Neurostimulation of the Retina Using a Multilayer Organic Semiconductor Device.
A multilayer organic semiconductor structure was developed for effective wireless stimulation of cells, including neurons. The parameters of the photovoltage and photocurrent generated on irradiation of the structure with short pulses of red light at a safe radiation intensity were studied. The effe...
| Publicado en: | Biomedical Engineering Vol. 57; no. 2; pp. 81 - 85 |
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| Autores principales: | , , , |
| Formato: | pictorial tables/charts Journal Article |
| Publicado: |
Springer Nature
Jul2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164579959&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164579959 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00063398 N96 jtl: Biomedical Engineering issn: 00063398 maglogo: N pubinfo: dt: Jul2023 vid: 57 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 164579959 164322886 164579959 164579959 10.1007/s10527-023-10273-z 164579959 ppf: 81 ppct: 4 formats: tig: atl: Wireless Optoelectronic Neurostimulation of the Retina Using a Multilayer Organic Semiconductor Device. aug: au: Markov, A. G. Gerasimenko, A. Yu. Selishchev, S. V. Telyshev, D. V. affil: Institute of Bionic Technologies and Engineering, Digital Design and Personalized Healthcare World-Level Science Center, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia sug: subj: Retinal Ganglion Cells Physiology Deep Brain Stimulation Equipment and Supplies Electric Stimulation Methods Electronics Neurons Electrophysiology Photophobia Photoreceptors Molecular Structure ab: A multilayer organic semiconductor structure was developed for effective wireless stimulation of cells, including neurons. The parameters of the photovoltage and photocurrent generated on irradiation of the structure with short pulses of red light at a safe radiation intensity were studied. The effectiveness of multilayer organic semiconductor structures was confirmed by photostimulation of light-insensitive areas of the retina. An organic structure as small as 50 μm was found to be able to generate action potentials efficiently. These results support the conclusion that multilayer organic semiconductor device technology can not only achieve parity with modern silicon devices, but can also surpass them in terms of miniaturization and performance. The results obtained here are important for clinical medicine and research activities. pubtype: Academic Journal doctype: pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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