The impact of obesity on ocular hemodynamics and choroidal thickness.
Background: Obesity affects microvascular structures. The effect of obesity on the ocular vascular system can be evaluated by changes in the choroidal thickness (CT) and retrobulbar blood flow (RBF). Objectives: To evaluate the CT and RBF parameters in obese patients with various body mass index (BM...
| Publicado en: | Therapeutic Advances in Ophthalmology pp. 1 - 13 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
6/30/2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164657098&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164657098 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 25158414 LAW0 jtl: Therapeutic Advances in Ophthalmology issn: 25158414 maglogo: Y pubinfo: dt: 6/30/2023 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 164657098 164657098 164657098 10.1177/25158414231180985 164657098 ppf: 1 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The impact of obesity on ocular hemodynamics and choroidal thickness. aug: au: Tufek, Melek Nalcacioglu, Pinar Capraz, Mustafa Varol, Kenan Kaya, Ahmet Turan Aydın, Nihat Kara, Caner affil: Conceptualization, Department of Ophthalmology, Amasya University, Sabuncuoglu Serafeddin Training and Research Hospital, Kirazlıdere Mahallesi, Asya Sokak, Amasya, Eyalet/Yerleske 05100, Turkey sug: subj: Obesity Complications Eye Blood Supply Blood Circulation Physiology Hemodynamics Eye Anatomy and Histology Intraocular Pressure Human Prospective Studies Female Body Mass Index Retinal Artery Anatomy and Histology Ophthalmic Artery Anatomy and Histology Ultrasonography, Doppler Tonometry Tomography, Optical Coherence Descriptive Statistics Female ab: Background: Obesity affects microvascular structures. The effect of obesity on the ocular vascular system can be evaluated by changes in the choroidal thickness (CT) and retrobulbar blood flow (RBF). Objectives: To evaluate the CT and RBF parameters in obese patients with various body mass index (BMI) values and compare these parameters with normal weight, healthy subjects. Design: A prospective study. Methods: The study included 102 eyes of 102 female patients. Patients were divided into three groups according to BMI as group 1 with a BMI of 18.5–24.99 (n = 32), normal weight group; group 2 with a BMI of 30–34.99 (n = 35), as obese class I; and group 3 with a BMI of 35–39.99 (n = 35), as obese class II. The peak systolic velocity (PSV), end-diastolic velocity (EDV), resistive index, and pulsatility index values of the central retinal artery (CRA) and ophthalmic artery (OA) were evaluated with color Doppler ultrasonography. CT was measured at the subfoveal area and at 500-µm intervals nasal and temporal to the fovea up to a distance of 1500 µm by using the enhanced depth imaging technique of optical coherence tomography. Intraocular pressure (IOP) was measured with a Goldmann applanation tonometry. Results: There was a significant difference in IOP values within the groups with the highest values in group 3 (17.6 ± 2.1 mmHg) and the lowest in group 1 (12.4 ± 1.7 mmHg). The CT in groups 2 and 3 was found to be statistically significantly lower than that in group 1 at all measurement points (p < 0.001). There was a statistically significant negative correlation between CT at all measurement points and BMI (p < 0.001). The mean CRA PSV, EDV, and OA EDV values were statistically significantly lower in each obese group than those values in group 1 (p < 0.001). The OA PSV values were significantly lower in group 3 (36.5 ± 5.9 cm/s) than those in group 2 (43.8 ± 4 cm/s) and group 1 (44.6 ± 5.2 cm/s) (p < 0.001). Also, significant associations were found between BMI and CRA PSV, CRA EDV, and OA PSV values (p < 0.001). Conclusion: Obesity may predispose to eye pathologies by changing the ocular vascular circulation. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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