How and when are topological explanations complete mechanistic explanations? The case of multilayer network models.

The relationship between topological explanation and mechanistic explanation is unclear. Most philosophers agree that at least some topological explanations are mechanistic explanations. The crucial question is how to make sense of this claim. Zednik (Philos Psychol 32(1):23–51, 2019, ) argues that...

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Publicado en:Synthese Vol. 202; no. 1; pp. 1 - 22
Autores principales: Krickel, Beate, de Bruin, Leon, Douw, Linda
Formato: Artículo
Publicado: Springer Nature Jul2023
Acceso en línea:Ver este registro en EBSCOhost
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        atl: How and when are topological explanations complete mechanistic explanations? The case of multilayer network models.
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          Krickel, Beate
          de Bruin, Leon
          Douw, Linda
        affil:
          Institute of History and Philosophy of Science, Technology, and Literature, Technical University Berlin, Straße des 17. Juni 135, 10623, Berlin, Germany
          Department of Anatomy & Neurosciences, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands
      sug:
      keyword:
        Mechanistic completeness
        Mechanistic explanation
        Multilayer models
        Network models
        Neuroscientific explanation
        Topological explanation
      ab: The relationship between topological explanation and mechanistic explanation is unclear. Most philosophers agree that at least some topological explanations are mechanistic explanations. The crucial question is how to make sense of this claim. Zednik (Philos Psychol 32(1):23–51, 2019, ) argues that topological explanations are mechanistic if they (i) describe mechanism sketches that (ii) pick out organizational properties of mechanisms. While we agree with Zednik’s conclusion, we critically discuss Zednik’s account and show that it fails as a general account of how and when topological explanations are mechanistic. First, if topological explanations were just mechanism sketches, this implies that they could be enriched by replacing topological terms with mechanistic detail. This, however, conflicts how topological explanations are used in scientific practice. Second, Zednik’s account fails to show how topological properties can be organizational properties of mechanisms that have a place in mechanistic explanation. The core issue is that Zednik’s account ignores that topological properties often are global properties while mechanistic explanantia refer to local properties. We demonstrate how these problems can be solved by a recent account of mechanistic completeness (Craver and Kaplan in Br J Philos Sci 71(1):287–319, 2020, ; Kohár and Krickel in Calzavarini and Viola (eds) Neural mechanisms—new challenges in the philosophy of neuroscience, Springer, New York, 2021, ) and use a multilayer network model of Alzheimer’s Disease to illustrate this.
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    language: English
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