Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research.
Objective: The present study aims to examine investigation the α-actinin-3 (ACTN3) gene polymorphism (rs1815739) and functional movement screen (FMS) values in young runners competing at the national level. Material and Methods: Forty-five young runners (29 male 64.4%, 16 female 35.6%) competing at...
| Publicado en: | Turkiye Klinikleri Journal of Sports Sciences Vol. 15; no. 2; pp. 223 - 230 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Turkiye Klinikleri
2023
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164677389&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164677389 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13080938 BE7G jtl: Turkiye Klinikleri Journal of Sports Sciences issn: 13080938 maglogo: N pubinfo: dt: 2023 vid: 15 iid: 2 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 164677389 164677389 164677389 10.5336/sportsci.2022-94239 164677389 ppf: 223 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Investigation of the ACTN3 Gene Polymorphism (rs1815739) and FMS Values in Young Runners: Cross-Sectional Research. aug: au: BULGAY, Celal BAYRAKTAR, Işık ÖDEMİŞ, Meriç YILDIRIM, Damla Selin ERGÜN, Mehmet Ali CERİT, Mesut ULUCAN, Korkut affil: Department of Physical Education and Sports Teaching, Bingöl University Faculty of Sport Sciences, Bingöl, Türkiye sug: subj: Muscle Proteins Polymorphism, Genetic Evaluation Athletic Performance Evaluation Movement Evaluation Functional Assessment Athletes, Elite Human Male Female Young Adult Cross Sectional Studies Genotype DNA Analysis Polymerase Chain Reaction Methods Functional Status Transcription Factors Descriptive Statistics Comparative Studies Data Analysis Software Turkiye Male Female ab: Objective: The present study aims to examine investigation the α-actinin-3 (ACTN3) gene polymorphism (rs1815739) and functional movement screen (FMS) values in young runners competing at the national level. Material and Methods: Forty-five young runners (29 male 64.4%, 16 female 35.6%) competing at the national level in different clubs affiliated to the Turkish Athletic Federation and training regularly at least 5 days a week voluntarily participated in the study. The DNA isolation of oral swab samples was carried out using the spin column (MN Macherey-Nagel, Germany) method. The genotyping process was performed using the real-time polymerase chain reaction method. Results: The FMS test battery was used to determine the functional capacity. According to the findings obtained, it was determined that in the FMS evaluation of the female runners, the runners with the CC genotype had a significantly higher mean score compared to the runners with the CT genotype (p<0.033) while in the male runners, the runners with the CT genotype had a significantly higher mean score compared to the runners with the TT genotype (p<0.031). However, in the FMS evaluation of the overall runners, no significant difference was found (p>0.205). Conclusion: It is thought that the FMS test battery and the ACTN3 gene polymorphism, which is among the important variables responsible for non-impact injuries, can be effective in the level of muscle damage, the type of muscle injury, the prediction of injuries and reducing the risk factors that may cause injuries. Amaç: Sunulan çalışma, ulusal düzeyde yarışan genç koşucularda α-aktinin-3 [α-actinin-3 (ACTN3)] gen polimorfizmi (rs1815739) ve fonksiyonel hareket analizi [functional movement screen (FMS)] değerlerini incelemeyi amaçlamaktadır. Gereç ve Yöntemler: Araştırmaya, Türkiye Atletizm Federasyonuna bağlı farklı kulüplerde lisanslı olarak ulusal düzeyde yarışan, haftada en az 5 gün düzenli antrenman yapan 45 genç koşucu (29'u erkek %64,4, 16'sı kadın %35,6) gönüllü olarak katılmıştır. Ağız sürüntü örneklerinin DNA izolasyonu spin kolon (MN Macherey-Nagel, Almanya) yöntemi ile gerçekleştirilmiştir. Genotipleme işlemi gerçek zamanlı polimeraz zincir reaksiyonu metodu ile gerçekleştirilmiştir. Fonksiyonel kapasitenin belirlenmesi için FMS test bataryası kullanılmıştır. Bulgular: Elde edilen bulgulara göre kadın koşucuların FMS değerlendirmesinde, CC genotipe sahip koşucuların ortalama puanının CT genotipe sahip koşuculardan (p<0,033), erkek koşucularda ise CT genotipe sahip koşucuların ortalama puanı TT genotipe sahip koşuculardan (p<0,031) anlamlı bir şekilde daha yüksek olduğu tespit edilmiştir. Ancak toplam koşucuların FMS değerlendirmesinde genotipe göre anlamlı bir farklılık tespit edilmemiştir (p>0,205). Sonuç: Darbelere bağlı olmayan yaralanmalardan sorumlu önemli değişkenlerden ACTN3 gen polimorfizmi ve FMS test bataryasının, koşucularda kas hasarı düzeyine, kas yaralanma tipine, yaralanmaların önceden tahmin edilmesine ve yaralanmalara neden olabilecek risk faktörlerinin azaltılmasına etkili olacağı düşünülmektedir. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|