Iranian Consensus Guideline for Pharmacotherapy with Biologics and Small Molecules Drugs in Adults with Inflammatory Bowel Diseases.
Background: Pharmacotherapy with biologics and small molecules, as the more effective therapies for moderate to severe ulcerative colitis (UC) and Crohn's disease (CD), is complex. Choosing the best methods for their utilization in order to induce and maintain remission are critical for practicing g...
| Publicado en: | Middle East Journal of Digestive Diseases Vol. 15; no. 2; pp. 83 - 107 |
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| Autores principales: | , , , , , , , , , |
| Formato: | glossary practice guidelines research tables/charts Journal Article |
| Publicado: |
Iranian Association of Gastroenterology & Hepatology
Apr2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164677408&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164677408 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20085230 BG4K jtl: Middle East Journal of Digestive Diseases issn: 20085230 maglogo: N pubinfo: dt: Apr2023 vid: 15 iid: 2 pid: 70725 pub: Iranian Association of Gastroenterology & Hepatology artinfo: ui: 164677408 164677408 164677408 10.34172/mejdd.2023.327 164677408 ppf: 83 ppct: 24 formats: fmt: @attributes: type: P tig: atl: Iranian Consensus Guideline for Pharmacotherapy with Biologics and Small Molecules Drugs in Adults with Inflammatory Bowel Diseases. aug: au: Khoshnam-Rad, Niloofar Vahedi, Homayoon Sadegh, Anahita Rastegarpanah, Mansoor Namaz, Soha Anushiravani, Amir Sima, Ali Reza Shahrokh, Shabnam Alatab, Sudabeh Malekzadeh, Reza affil: Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran sug: subj: Inflammatory Bowel Diseases Drug Therapy Consensus Practice Guidelines Iran Small Molecules Therapeutic Use Biological Products Therapeutic Use Human Male Female Adult Iran Delphi Technique Protocols Voting Judgment Drug Efficacy Patient Safety Drug Therapy, Combination Tumor Necrosis Factor Inhibitors Crohn Disease Adult: 19-44 years Male Female ab: Background: Pharmacotherapy with biologics and small molecules, as the more effective therapies for moderate to severe ulcerative colitis (UC) and Crohn's disease (CD), is complex. Choosing the best methods for their utilization in order to induce and maintain remission are critical for practicing gastroenterologists. We aimed to develop an Iranian consensus on the management of inflammatory bowel disease (IBD) patients with biologics and small molecules. Methods: A Delphi consensus was undertaken by experts who performed a literature summary and voting process. Quality of evidence was assessed using the Grading and Recommendations Assessment, Development, and Evaluation; and an additional risk of bias-protocol. Results: Following an extensive search of the literature, 219 studies were used to determine the quality of the evidence. After three rounds of voting, consensus (defined as ≥ 80% agreement) was reached for 87 statements. Conclusion: We considered different aspects of pharmacotherapy in this consensus. This guideline, along with clinical judgment, can be used to optimize management of IBD patients. pubtype: Academic Journal doctype: glossary practice guidelines research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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