Cross-subject variability of the optic radiation anatomy in a cohort of 1065 healthy subjects.
Introduction: Optic radiations are tracts of particular interest for neurosurgery, especially for temporal lobe resection, because their lesion is responsible for visual field defects. However, histological and MRI studies found a high inter-subject variability of the optic radiation anatomy, especi...
| Publicado en: | Surgical & Radiologic Anatomy Vol. 45; no. 7; pp. 849 - 859 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jul2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164680392&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164680392 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09301038 O1L jtl: Surgical & Radiologic Anatomy issn: 09301038 maglogo: N pubinfo: dt: Jul2023 vid: 45 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 164680392 163758291 10.1007/s00276-023-03161-4 164680392 ppf: 849 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Cross-subject variability of the optic radiation anatomy in a cohort of 1065 healthy subjects. aug: au: Herlin, B. Uszynski, I. Chauvel, M. Poupon, C. Dupont, S. affil: BAOBAB, NeuroSpin, Université Paris-Saclay, CNRS, CEA, Gif-Sur-Yvette, France sug: ab: Introduction: Optic radiations are tracts of particular interest for neurosurgery, especially for temporal lobe resection, because their lesion is responsible for visual field defects. However, histological and MRI studies found a high inter-subject variability of the optic radiation anatomy, especially for their most rostral extent inside the Meyer's temporal loop. We aimed to better assess inter-subject anatomical variability of the optic radiations, in order to help to reduce the risk of postoperative visual field deficiencies. Methods: Using an advanced analysis pipeline relying on a whole-brain probabilistic tractography and fiber clustering, we processed the diffusion MRI data of the 1065 subjects of the HCP cohort. After registration in a common space, a cross-subject clustering on the whole cohort was performed to reconstruct the reference optic radiation bundle, from which all optic radiations were segmented on an individual scale. Results: We found a median distance between the rostral tip of the temporal pole and the rostral tip of the optic radiation of 29.2 mm (standard deviation: 2.1 mm) for the right side and 28.8 mm (standard deviation: 2.3 mm) for the left side. The difference between both hemispheres was statistically significant (p = 1.10–8). Conclusion: We demonstrated inter-individual variability of the anatomy of the optic radiations on a large-scale study, especially their rostral extension. In order to better guide neurosurgical procedures, we built a MNI-based reference atlas of the optic radiations that can be used for fast optic radiation reconstruction from any individual diffusion MRI tractography. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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