Electrically evoked auditory cortical responses elicited from individually fitted stimulation parameters in cochlear implant users.

To investigate electrically evoked auditory cortical responses (eACR) elicited from the stimulation of intracochlear electrodes based on individually fitted stimulation parameters in cochlear implant (CI) users. An eACR setup based on individual fitting parameters is proposed. A 50-ms alternating bi...

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Publicado en:International Journal of Audiology Vol. 62; no. 7; pp. 650 - 659
Autores principales: Callejón-Leblic, María A., Barrios-Romero, María M., Kontides, Alejandra, Sánchez-Gómez, Serafín, Beynon, Andy J.
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jul2023
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Journal of Audiology
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      dt: Jul2023
      vid: 62
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/14992027.2022.2062578
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        atl: Electrically evoked auditory cortical responses elicited from individually fitted stimulation parameters in cochlear implant users.
      aug:
        au:
          Callejón-Leblic, María A.
          Barrios-Romero, María M.
          Kontides, Alejandra
          Sánchez-Gómez, Serafín
          Beynon, Andy J.
        affil: Department of Otolaryngology, Head and Neck Surgery, Virgen Macarena University Hospital, Seville, Spain
      sug:
        subj:
          Electric Stimulation
          Evoked Potentials, Auditory
          Auditory Perception
          Cochlear Implant
          Human
          Descriptive Statistics
          Male
          Female
          Adult
          Middle Age
          Aged
          Hearing Disorders Surgery
          Data Analysis Software
          One-Way Analysis of Variance
          Post Hoc Analysis
          T-Tests
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: To investigate electrically evoked auditory cortical responses (eACR) elicited from the stimulation of intracochlear electrodes based on individually fitted stimulation parameters in cochlear implant (CI) users. An eACR setup based on individual fitting parameters is proposed. A 50-ms alternating biphasic pulse train was used to stimulate apical, medial, and basal electrodes and to evoke auditory cortical potentials (N1-P2 complex). The eACR setup proposed was validated with 14 adult CI users. Individual and grand-average eACR waveforms were obtained. The eACR amplitudes were lower in the basal than in the apical and medial regions. Earlier N1 latencies were found in CI users with lower maximum comfortable loudness levels and shorter phase duration in response to apical stimulation, while medial and basal stimulation resulted in earlier N1 latencies and larger N1-P2 amplitudes in users with longer CI experience. eACR could be elicited by direct intracochlear stimulation using individual fitting parameters with a success rate of 71%. The highest cortical peak-to-peak amplitudes were obtained in response to apical stimulation. Unlike the P2, the N1 component appeared to be a consistent cortical potential to determine eACR and gain knowledge of the auditory processing beyond the cochlea in CI users. eACR can be elicited through direct stimulation of intracochlear electrodes. Stimulation of apical and medial regions yielded the highest N1-P2 amplitudes. CI users with lower maximum comfortable loudness levels had shorter N1 latencies during apical stimulation. The present dataset of mainly well-performing CI users suggests better cortical processing, that is, higher amplitudes and shorter latencies of N1. The N1 potential appears a more consistent and reliable potential than the P2 to determine eACR responses in CI users.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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