Geographical Differences of Risk of Asthma and Allergic Rhinitis according to Urban/Rural Area: a Systematic Review and Meta-analysis of Cohort Studies.

Several studies have demonstrated an association between the risk asthma/allergic rhinitis and the environment. However, to date, no systematic review or meta-analysis has investigated these factors. We conducted a systematic review and meta-analysis to assess the association between urban/rural liv...

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Publicado en:Journal of Urban Health Vol. 100; no. 3; pp. 478 - 493
Autores principales: Song, Mincheol, Hwang, Seohyeon, Son, Eunjeong, Yeo, Hye Ju, Cho, Woo Hyun, Kim, Tae Woo, Kim, Kihun, Lee, Dongjun, Kim, Yun Hak
Formato: Artículo
Publicado: Springer Nature Jun2023
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2023
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        atl: Geographical Differences of Risk of Asthma and Allergic Rhinitis according to Urban/Rural Area: a Systematic Review and Meta-analysis of Cohort Studies.
      aug:
        au:
          Song, Mincheol
          Hwang, Seohyeon
          Son, Eunjeong
          Yeo, Hye Ju
          Cho, Woo Hyun
          Kim, Tae Woo
          Kim, Kihun
          Lee, Dongjun
          Kim, Yun Hak
        affil:
          Department of Medicine, Pusan National University, Yangsan, Republic of Korea
          Division of Respiratory and Allergy, Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea
          Department of Orthopaedic Surgery, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea
          Department of Biomedical Informatics, School of Medicine, Pusan National University, Yangsan, Republic of Korea
          Department of Anatomy, School of Medicine, Pusan National University, Yangsan, Republic of Korea
          Department of Convergence Medicine, School of Medicine, Pusan National University, 50612, Yangsan, Republic of Korea
      su:
        Rural geography
        Allergic rhinitis
        Asthma in children
        Respiratory diseases
        Asthma
      sug:
        subj:
          Rural geography
          Allergic rhinitis
          Asthma in children
          Respiratory diseases
          Asthma
      keyword:
        Meta-analysis
        Rural
        Systematic review
        Urban
        Meta-analysis
        Rural
        Systematic review
        Urban
      ab: Several studies have demonstrated an association between the risk asthma/allergic rhinitis and the environment. However, to date, no systematic review or meta-analysis has investigated these factors. We conducted a systematic review and meta-analysis to assess the association between urban/rural living and the risk of asthma and allergic rhinitis. We searched the Embase and Medline databases for relevant articles and included only cohort studies to observe the effects of time-lapse geographical differences. Papers containing information on rural/urban residence and respiratory allergic diseases were eligible for inclusion. We calculated the relative risk (RR) and 95% confidence interval (CI) using a 2 × 2 contingency table and used random effects to pool data. Our database search yielded 8388 records, of which 14 studies involving 50,100,913 participants were finally included. The risk of asthma was higher in urban areas compared to rural areas (RR, 1.27; 95% CI, 1.12–1.44, p < 0.001), but not for the risk of allergic rhinitis (RR, 1.17; 95% CI, 0.87–1.59, p = 0.30). The risk of asthma in urban areas compared to rural areas was higher in the 0–6 years and 0–18 years age groups, with RRs of 1.21 (95% CI, 1.01–1.46, p = 0.04) and 1.35 (95% CI, 1.12–1.63, p = 0.002), respectively. However, there was no significant difference in the risk of asthma between urban and rural areas for children aged 0–2 years, with a RR of 3.10 (95% CI, 0.44–21.56, p = 0.25). Our study provides epidemiological evidence for an association between allergic respiratory diseases, especially asthma, and urban/rural living. Future research should focus on identifying the factors associated with asthma in children living in urban areas. The review was registered in PROSPERO (CRD42021249578).
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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