Effect of cycloplegic agents (1% cyclopentolate hydrochloride and 1% tropicamide) on anterior segment parameters.

Background: Cycloplegic drops are commonly used in ophthalmology practice. Changes in anterior segment parameters may occur after cycloplegia. These changes can be evaluated with corneal topography. Objective: This study aimed to compare the effects of 1% cyclopentolate hydrochloride and 1% tropicam...

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Publicado en:Therapeutic Advances in Ophthalmology pp. 1 - 10
Autores principales: Duran, Mustafa, Cevher, Selim
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. 7/8/2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/8/2023
      pid: 344
      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Effect of cycloplegic agents (1% cyclopentolate hydrochloride and 1% tropicamide) on anterior segment parameters.
      aug:
        au:
          Duran, Mustafa
          Cevher, Selim
        affil: Conceptualization, Department of Ophthalmology, Specialist of Ophthalmology, Minister of Health Hitit University Erol Olçok Education and Research Hospital, Çorum, Turkey
      sug:
        subj:
          Mydriatics Pharmacodynamics
          Acids, Carbocyclic Therapeutic Use
          Diagnostic Imaging Methods
          Mydriatics Administration and Dosage
          Anterior Eye Segment Drug Effects
          Ophthalmology
          Corneal Topography
          Cross Sectional Studies
          Intraocular Pressure
          Cataract Extraction
          Lenses, Intraocular
          Keratoconus
          Human
          Male
          Female
          Young Adult
          Adult
          Middle Age
          Data Analysis Software
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: Cycloplegic drops are commonly used in ophthalmology practice. Changes in anterior segment parameters may occur after cycloplegia. These changes can be evaluated with corneal topography. Objective: This study aimed to compare the effects of 1% cyclopentolate hydrochloride and 1% tropicamide on anterior segment parameters using the Sirius Scheimpflug imaging technique. Design: A cross-sectional study. Methods: One hundred twenty eyes of sixty healthy volunteers with spherical equivalent (SE) values of 0 to ±1 diopter (D) were studied. The right eye of each subject had instillation of cyclopentolate hydrochloride 1% (Group 1) and the left eye of each subject had instillation of tropicamide 1% (Group 2). SE, intraocular pressure, and corneal topography measurements were performed before and 40 min after instillation were compared. Results: In Group 1, SE, aqueous depth, anterior chamber depth, iridocorneal angle (ICA), anterior chamber volume (ACV), and pupil size (PS) values were significantly increased (p < 0.001, p = 0.01, p < 0.001, p = 0.03, p < 0.001, and p < 0.001, respectively). In Group 2, SE, ICA, ACV, and PS were significantly increased (p < 0.001 for all). Keratometric values (K1 and K2) and central corneal thickness changed insignificantly in both groups (p > 0.05). The effects of the two administered agents on all parameters were similar (p > 0.05). Conclusions: Cyclopentolate hydrochloride and tropicamide affected SE, ICA, ACV, and PS values significantly. These parameters are important in intraocular lens (IOL) power calculations. PS is also important in refractive surgery and cataract surgery with multifocal IOL implantation. Although there was an insignificant difference between the agents, the effects of tropicamide on the parameters were smaller than those of cyclopentolate.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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