VenUS 6 -- A randomised controlled trial of compression therapies for the treatment of venous leg ulcers: Study design and update.
Background Venous leg ulcers (VLU) are common wounds, mainly in the gaiter region of the leg. Compression therapy is an effective treatment for reducing the time to healing of VLU. The four-layer bandage and two-layer hosiery protocols are supported by good evidence for clinical and cost effectivene...
| Publicado en: | Journal of Wound Management Vol. 23; no. 1; pp. 13 - 18 |
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| Autores principales: | , , , , , |
| Formato: | protocol tables/charts Journal Article |
| Publicado: |
Cambridge Publishing
Apr2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164822732&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164822732 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 27885771 MZEQ jtl: Journal of Wound Management issn: 27885771 maglogo: N pubinfo: dt: Apr2022 vid: 23 iid: 1 pid: 66266 pub: Cambridge Publishing artinfo: ui: 164822732 164822732 164822732 10.35279/jowm2022.23.01.02 164822732 ppf: 13 ppct: 5 formats: fmt: @attributes: type: P tig: atl: VenUS 6 -- A randomised controlled trial of compression therapies for the treatment of venous leg ulcers: Study design and update. aug: au: Zahra, Sabeen Arundel, Catherine Jones, Katherine Davill, Tom Roberts, Gareth Dumville, Jo affil: York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, YO10 5DD sug: subj: Compression Therapy Methods Venous Ulcer Therapy Cost Effectiveness Analysis Health Care Costs Evaluation Medical Practice, Evidence-Based Elastic Bandages Treatment Outcomes Wound Healing Evaluation Bandaging Techniques Randomized Controlled Trials Multicenter Studies ab: Background Venous leg ulcers (VLU) are common wounds, mainly in the gaiter region of the leg. Compression therapy is an effective treatment for reducing the time to healing of VLU. The four-layer bandage and two-layer hosiery protocols are supported by good evidence for clinical and cost effectiveness. There is more limited evidence for other treatments, such as the two-layer bandage and compression wraps. Robust evidence is required to compare the clinical and cost effectiveness of these and to investigate which is the best compression treatment for reducing time to healing of VLU whilst offering value for money. Aim VenUS 6 aims to investigate the clinical and cost effectiveness of evidence-based compression, twolayer bandage and compression wraps for time to healing of VLU. Method This multicentre, pragmatic, three-arm parallel group study aims to recruit 675 eligible participants aged ≥18 years with at least one VLU, and who can tolerate full compression and give written consent. Participants are allocated 1:1:1 to receive evidence-based compression, two-layer bandage or compression wrap. Participants are followed up with weekly assessments until the participant's reference leg is ulcer-free and no further nursing assessments are required to treat the leg. Reference ulcer healing is confirmed by a healthcare professional/treating nurse. Participant-reported outcomes are collected at baseline and at 1, 3, 6 and 12 months. The primary outcome is time to healing of the reference ulcer. Secondary outcomes include clinical events and participant-reported ulcer related pain, quality of life, treatment adherence and resource use. pubtype: Academic Journal doctype: protocol tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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