Development and assessment of the performance of a shared ventilatory system that uses clinically available components to individualize tidal volumes.
Objectives: To develop and assess a system for shared ventilation using clinically available components to individualize tidal volumes. Design: Evaluation and in vitro validation study Setting: Ventilator shortage during the SARS-CoV-2 pandemic. Participants: The team consisted of physicians, bioeng...
| Publicado en: | BMC Anesthesiology Vol. 23; no. 1; pp. 1 - 12 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
BioMed Central
7/15/2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164945019&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164945019 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14712253 1CH3 jtl: BMC Anesthesiology issn: 14712253 maglogo: N pubinfo: dt: 7/15/2023 vid: 23 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 164945019 164945019 164945019 10.1186/s12871-023-02200-2 164945019 ppf: 1 ppct: 11 formats: tig: atl: Development and assessment of the performance of a shared ventilatory system that uses clinically available components to individualize tidal volumes. aug: au: Hannon, David M. Jones, Tim Conolly, Jack Judge, Conor Iqbal, Talha Shahzad, Atif Madden, Michael Kirrane, Frank Conneely, Peter Harte, Brian H. O'Halloran, Martin Laffey, John G. affil: Department of Anaesthesia, School of Medicine, Galway University Hospitals, University of Galway, Galway, Ireland sug: subj: COVID-19 Therapy Ventilators, Mechanical Tidal Volume Respiration, Artificial Methods Equipment Design Instrument Validation Human In Vitro Studies Validation Studies Pilot Studies SARS-CoV-2 Disease Outbreaks Software Computers and Computerization Quality Assessment ab: Objectives: To develop and assess a system for shared ventilation using clinically available components to individualize tidal volumes. Design: Evaluation and in vitro validation study Setting: Ventilator shortage during the SARS-CoV-2 pandemic. Participants: The team consisted of physicians, bioengineers, computer programmers, and medical technology professionals. Methods: Using clinically available components, a system of ventilation consisting of two ventilatory limbs was assembled and connected to a ventilator. Monitors for each limb were developed using open-source software. Firstly, the effect of altering ventilator settings on tidal volumes delivered to each limb was determined. Secondly, the impact of altering the compliance and resistance of one limb on the tidal volumes delivered to both limbs was analysed. Experiments were repeated three times to determine system variability. Results: The system permitted accurate and reproducible titration of tidal volumes to each limb over a range of ventilator settings and simulated lung conditions. Alteration of ventilator inspiratory pressures, of respiratory rates, and I:E ratio resulted in very similar tidal volumes delivered to each limb. Alteration of compliance and resistance in one limb resulted in reproducible alterations in tidal volume to that test lung, with little change to tidal volumes in the other lung. All tidal volumes delivered were reproducible. Conclusions: We demonstrate the reliability of a shared ventilation system assembled using commonly available clinical components that allows titration of individual tidal volumes. This system may be useful as a strategy of last resort for Covid-19, or other mass casualty situations, where the need for ventilators exceeds supply. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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