EP127 WARFARIN INDUCED SKIN NECROSIS AND DIFFERENTIAL DIAGNOSES - A GUIDE TO EARLY DIAGNOSIS AND TREATMENT...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy
Aim: In rare cases warfarin paradoxically induces hypercoagulation, multiple microthrombi and necrotic skin ulcers. Severe cases may lead to amputation or death. Thus, early treatment is imperative and possibly life- or limb saving. Warfarin induced skin necrosis (WISN) can be difficult to diagnose,...
| Publicado en: | Journal of Wound Management Vol. 24; no. 2; p. 101 |
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| Autores principales: | , |
| Formato: | abstract proceedings research Journal Article |
| Publicado: |
Cambridge Publishing
Jul2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164968841&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164968841 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 27885771 MZEQ jtl: Journal of Wound Management issn: 27885771 maglogo: N pubinfo: dt: Jul2023 vid: 24 iid: 2 pid: 66266 pub: Cambridge Publishing artinfo: ui: 164968841 164968841 164968841 164968841 ppf: 101 ppct: 0 formats: fmt: @attributes: type: P tig: atl: EP127 WARFARIN INDUCED SKIN NECROSIS AND DIFFERENTIAL DIAGNOSES - A GUIDE TO EARLY DIAGNOSIS AND TREATMENT...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy aug: au: Haahr, Ellen Prasad, Sumangali Chandra affil: University of Southern Denmark, Sundhedsvidenskabeligt Fakultet, Odense, Denmark sug: subj: Skin Pathology Necrosis Chemically Induced Necrosis Diagnosis Necrosis Therapy Warfarin Adverse Effects Diagnosis, Differential Methods Early Diagnosis Methods Congresses and Conferences Italy Italy ab: Aim: In rare cases warfarin paradoxically induces hypercoagulation, multiple microthrombi and necrotic skin ulcers. Severe cases may lead to amputation or death. Thus, early treatment is imperative and possibly life- or limb saving. Warfarin induced skin necrosis (WISN) can be difficult to diagnose, because of its rarity and many mimickers. The aim of this article is to establish diagnostic characteristics of Warfarin induced Skin Necrosis (WISN), with the intent of creating an easily accessible guide to aid physicians in early detection and treatment of WISN. The objective is to identify the differences in epidemiology, clinical and paraclinical findings between WISN and the differential diagnoses: heparin induced skin necrosis, calciphylaxis, pyoderma gangrenosum and antiphospholipid syndrome. Method: Literature available on PubMed was reviewed to identify clinical features of WISN and the differential diagnoses. Exclusion- and inclusion criteria were applied to 465 articles. The included articles were reviewed and clinical features of the diseases were summarised and compared. Results / Discussion: The five diagnoses mentioned have various clinical expressions, some rare, some common. Differentiation between the aforementioned diseases can be challenging. However, we were able to find dissimilarities in the histological, clinical and paraclinical characteristics, which might aid physicians in diagnosing WISN. Furthermore, we found consensus on treatment within the literature. Conclusion: These diseases are rare, but nonetheless require early therapeutic treatment to minimize sequelae and potentially save the patient's limb or life. Treatment depends on the diagnosis, but all patients are given conservative wound care and may need surgical intervention. pubtype: Academic Journal doctype: abstract proceedings research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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