EP458 CLINICAL CASE SERIES: USE OF RECOMBINANT HUMAN COLLAGEN MATRIX FOR THE MANAGEMENT OF CHRONIC WOUNDS OF THE FOOT...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy
Aim: To present two clinical cases of patients with chronic neuropathic wounds of the foot, which were treated using a single application of human recombinant type I collagen produced in plants. Method: Two patients were treated in the outpatient department of Hospital of Lithuanian University of He...
| Published in: | Journal of Wound Management Vol. 24; no. 2; p. 295 |
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| Main Authors: | , |
| Format: | abstract case study proceedings Journal Article |
| Published: |
Cambridge Publishing
Jul2023
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=164969158&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 164969158 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 27885771 MZEQ jtl: Journal of Wound Management issn: 27885771 maglogo: N pubinfo: dt: Jul2023 vid: 24 iid: 2 pid: 66266 pub: Cambridge Publishing artinfo: ui: 164969158 164969158 164969158 164969158 ppf: 295 ppct: 0 formats: fmt: @attributes: type: P tig: atl: EP458 CLINICAL CASE SERIES: USE OF RECOMBINANT HUMAN COLLAGEN MATRIX FOR THE MANAGEMENT OF CHRONIC WOUNDS OF THE FOOT...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy aug: au: Markeviciute, Medeine Zacharevskij, Ernest affil: Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Department of Plastic and Reconstructive Surgery, Kaunas, Lithuania sug: subj: Wounds, Chronic Therapy Foot Ulcer Therapy Collagen Therapeutic Use Recombinant Proteins Therapeutic Use Congresses and Conferences Italy Italy ab: Aim: To present two clinical cases of patients with chronic neuropathic wounds of the foot, which were treated using a single application of human recombinant type I collagen produced in plants. Method: Two patients were treated in the outpatient department of Hospital of Lithuanian University of Health Sciences Kaunas Clinics. First case: 20 year old female with 2x1.5cm chronic wound of the left foot present for 2 months, second case: 17 year old male with a chronic wound of the right foot 0.3x0.4cm, present for 10 months. Both patients had neuropathic chronic wounds of the sole of the foot due to lack of sensation in the limbs caused by myelomeningocele. Both wounds did not respond to debridement and treatment with hydrocolloid and foam dressings. Wounds were photographed and preliminary surgical debridement was performed followed by single application of recombinant human collagen matrix and secondary hydrocolloid dressing. Patients were followed up weekly for 4 weeks. Results / Discussion: Significant wound closure was noticed in both cases. In first case, full wound epithelization was seen after 2 weeks, with full wound closure after 1 month. In second case, significant wound reduction in depth and diameter (>80%) was seen within 2 weeks. No adverse effects were seen. Conclusion: Single use of recombinant human collagen matrix filler for chronic foot wounds may promote wound closure with minimal adverse events. Vergenix™ Flow Gel pubtype: Academic Journal doctype: abstract case study proceedings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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