EP500 TIBIAL ULCER MIMICKING PYODERMA GANGRENOSUM...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy.

Aim: Highlighting the diagnostic complexity of skin ulcers. Method: We present a 31-year-old female patient who came to the ulcer unit of "Andreas Syggros" Hospital suffering from a festering necrotic ulcer that appeared a year earlier. She provided a previous punch biopsy result which was compatibl...

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Publicado en:Journal of Wound Management Vol. 24; no. 2; p. 319
Autores principales: Zacharopoulou, Aikaterini, Sgontzou, Themis, Zouridaki, Eftychia
Formato: abstract case study proceedings Journal Article
Publicado: Cambridge Publishing Jul2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2023
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        atl: EP500 TIBIAL ULCER MIMICKING PYODERMA GANGRENOSUM...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy.
      aug:
        au:
          Zacharopoulou, Aikaterini
          Sgontzou, Themis
          Zouridaki, Eftychia
        affil: Andreas Syggros" Hospital, Dermatology
      sug:
        subj:
          Lymphoma, Large-Cell, Anaplastic Diagnosis
          Diagnosis, Differential
          Pyoderma Gangrenosum
          Skin Ulcer
          Tibia
          Congresses and Conferences Italy
          Italy
          Adult
          Female
          Biopsy
          Adult: 19-44 years
          Female
      ab: Aim: Highlighting the diagnostic complexity of skin ulcers. Method: We present a 31-year-old female patient who came to the ulcer unit of "Andreas Syggros" Hospital suffering from a festering necrotic ulcer that appeared a year earlier. She provided a previous punch biopsy result which was compatible with pyoderma gangrenosum. In accordance with the diagnosis, she was already treated with steroids, colchicine, and multiple antibiotics due to positive cultures for E. coli and Pseudomonas aeruginosa. These treatments had little or no response. Due to the atypical clinical presentation of a persistent ulcer and the later appearance of systemic symptoms, we proceeded to do a surgical wedge biopsy and an immunohistochemistry examination. Results / Discussion: The new biopsy was compatible with a diagnosis of T-cell non-Hodgkin lymphoma (ALK+ large cell lymphoma). Conclusion: In some cases, a punch biopsy may lead to a misdiagnosis, so it is useful to perform a surgical wedge biopsy. Physicians should therefore be alert when a skin lesion persists, because it may indicate the presence of a serious underlying systemic disease.
      pubtype: Academic Journal
      doctype:
        abstract
        case study
        proceedings
        Journal Article
      ougenre: Article
    language: English
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