OP086 PREDILECTION SITES AND COMORBIDITIES OF PYODERMA GANGRENOSUM: RESULTS OF A BICENTER STUDY OF 170 PATIENTS...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy

Aim: Pyoderma gangrenosum (PG) can nowadays be reliably diagnosed with the validated PARACELSUS score. Based on this score, patients with clearly diagnosed PG should be evaluated with regard to the disease characteristics. Method: In this study, data of patients from the University Hospitals of Esse...

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Published in:Journal of Wound Management Vol. 24; no. 2; p. 435
Main Authors: Moelleken, Maurice, Erfurt-Berge, Cornelia, Ronicke, Moritz, Busch, Dorothee, Hübner, Ursula Hertha, Hüsers, Jens, Przysucha, Mareike, Dissemond, Joachim
Format: abstract proceedings research Journal Article
Published: Cambridge Publishing Jul2023
Online Access:View this record in EBSCOhost
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      dt: Jul2023
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        atl: OP086 PREDILECTION SITES AND COMORBIDITIES OF PYODERMA GANGRENOSUM: RESULTS OF A BICENTER STUDY OF 170 PATIENTS...European Wound Management Association (EWMA) Conference, May 3-5, 2023, Milan, Italy
      aug:
        au:
          Moelleken, Maurice
          Erfurt-Berge, Cornelia
          Ronicke, Moritz
          Busch, Dorothee
          Hübner, Ursula Hertha
          Hüsers, Jens
          Przysucha, Mareike
          Dissemond, Joachim
        affil: University Hospital of Essen, Dermatology, Venerology and Allergology, Essen, Germany
      sug:
        subj:
          Pyoderma Gangrenosum Diagnosis
          Comorbidity
          Disease Attributes
          Congresses and Conferences Italy
          Italy
      ab: Aim: Pyoderma gangrenosum (PG) can nowadays be reliably diagnosed with the validated PARACELSUS score. Based on this score, patients with clearly diagnosed PG should be evaluated with regard to the disease characteristics. Method: In this study, data of patients from the University Hospitals of Essen and Erlangen from the last 20 years were retrospectively analysed, in which the diagnosis PG could be clearly confirmed with the help of the PARACELSUS score. Results / Discussion: A total of 170 patients, 49 men (29%) and 121 women (71%) could be included in this analysis. The mean age at first manifestation was 55 years. The predilection sites were identified as the lower legs in 80.6% of the patients and here the extensor sides in 75.2%. Recurrences were seen in 28.8% of the patients, 38.8% in the same and 73.5% in another site. A pathergy phenomenon could be elicited in 42.4% of the patients, 23.6% due to insect bites and 80.6% due to trauma/surgery. Associated systemic diseases were 18.0% inflammatory bowel disease (11.0% Crohn's disease, 7.0% ulcerative colitis), 17.0% neoplasia (13.0% solid tumors, 4.0% hemato-oncologic diseases), 9.0% inflammatory dermatoses (5.0% psoriasis vulgaris, 4.0% hidradenitis suppurativa), and 7.0% rheumatoid arthritis. Conclusion: In this retrospective study, a collective of PG patients is analysed for the first time by means of PARACELSUS score with a high data quality regarding the correctly made diagnosis. It could be shown that especially the anterior sides of the lower sides are the predilection sites for PG. In addition, PG often arises from pathergy phenomena and associated systemic diseases often necessitate interdisciplinary treatment concepts.
      pubtype: Academic Journal
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    language: English
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