PHYSICAL EXERCISE AS A NON-PHARMACOLOGICAL AID IN THE TREATMENT OF ANXIETY DISORDER.

Anxiolytics such as with selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and benzodiazepines are often used to treat anxiety disorders. However, up to a third of patients do not respond to them, and they can have side effects. Regular physical activity, on...

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Publicado en:Brazilian Journal of Surgery & Clinical Research Vol. 43; no. 1; pp. 41 - 46
Autores principales: OLIVEIRA JUSTO, ALBERTO FERNANDO, LUCIANO AFONSO, MARIANA, LUCIANO AFONSO, PEDRO PAULO
Formato: Artículo
Publicado: Master Editora jun-ago2023
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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        atl: PHYSICAL EXERCISE AS A NON-PHARMACOLOGICAL AID IN THE TREATMENT OF ANXIETY DISORDER.
      aug:
        au:
          OLIVEIRA JUSTO, ALBERTO FERNANDO
          LUCIANO AFONSO, MARIANA
          LUCIANO AFONSO, PEDRO PAULO
        affil:
          Doutor em Farmacologia. Pesquisador do Departamento de Clínica Médica, Faculdade de Medicina da Universidade de São Paulo - FMUSP
          Doutora em Psicologia Social. Professora Assistente da Faculdade de Ciências Médicas da Universidade Cidade de São Paulo - UNICID
          Médico Psiquiatra. Doutorando em Farmacologia, Departamento de Farmacologia da Universidade de Campinas - UNICAMP. Professor Assistente de Psiquiatria da Universidade Nove de Julho - Campus Osasco
      su:
        Exercise
        Anxiety disorders treatment
        Brain function localization
        Tranquilizing drugs
        Drug side effects
      sug:
        subj:
          Exercise
          Anxiety disorders treatment
          Brain function localization
          Tranquilizing drugs
          Drug side effects
      keyword:
        Anxiety disorders
        Anxiolytics
        Treatment
      ab: Anxiolytics such as with selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and benzodiazepines are often used to treat anxiety disorders. However, up to a third of patients do not respond to them, and they can have side effects. Regular physical activity, on the other hand, can improve cardiovascular, urinary, and brain functions. Exercise increases nitric oxide production in endothelial cells, relaxes smooth muscle cells, inhibits platelets, and lowers low-density lipoprotein while increasing high-density lipoprotein. It also increases dopamine receptor affinity, leading to anxiolytic effects, and may link to noradrenaline levels in the brain, which also have anxiolytic effects. Exercise intensity can also regulate neurotransmitter release in the brain, which may have a role in anxiety. Meta-analyses and systematic reviews show the benefits of physical activity in treating anxiety disorders. Practicing physical activity reduces anxiety scores compared to sedentary individuals. Physical activity regulates anxiety through systemic and intracellular pathways, making it a potential alternative or complementary strategy for treating anxiety disorders. It has multiple benefits for both physical and mental health and has fewer side effects than anxiolytics.
      pubtype: Academic Journal
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    language: English
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      custom: Copyright of Brazilian Journal of Surgery & Clinical Research is the property of Master Editora and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use.
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      holder: Master Editora
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          year: 2023
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